Foucar E, Dehner L P
Arch Surg. 1979 Aug;114(8):959-63. doi: 10.1001/archsurg.1979.01370320091019.
Because renal cell carcinoma occasionally occurs in manifestations referable to a single metastatic lesion, there is a risk that a metastasis will be mistaken for the primary tumor. Histologic examination can compound the confusion, particularly when a clear cell carcinoma of the kidney metastasizes to an organ, such as lung, liver, adrenal, or skin, where clear cell tumors may occur as primary lesions. Although advanced renal cell carcinoma not infrequently involves the adrenal gland, the clinical and pathologic setting establishes the tumor in the adrenal as a metastasis. Two patients are described to illustrate what is to our knowledge the heretofore undescribed occurrence of renal cell carcinoma as a metastasis to the contralateral adrenal gland.
由于肾细胞癌偶尔会以单个转移病灶的表现出现，存在转移灶被误诊为原发肿瘤的风险。组织学检查可能会加剧这种混淆，尤其是当肾透明细胞癌转移至肺、肝、肾上腺或皮肤等可能发生透明细胞肿瘤作为原发性病变的器官时。尽管晚期肾细胞癌常累及肾上腺，但临床和病理情况可确定肾上腺的肿瘤为转移瘤。本文描述了两名患者，以说明据我们所知，肾细胞癌转移至对侧肾上腺这一此前未被描述的情况。
