Brooks N, Leech G, Leatham A
Br Heart J. 1979 Jun;41(6):637-46. doi: 10.1136/hrt.41.6.637.
High speed enchocardiograms of the mitral, tricuspid, and pulmonary valves were recorded with a simultaneous electrocardiogram and phonocardiogram in 20 patients with complete right bundle-branch block and in 67 normal subjects. Late opening of the pulmonary valve indicating late right ventricular ejection was found in all patients. In 8 patients with wide splitting of the first heart sound the late ejection was related mainly to delay in tricuspid valve closure, suggesting a late onset of the right ventricular pressure pulse. In 10 patients with a single first heart sound the delayed ejection was associated with a long interval between tricuspid valve closure and pulmonary valve opening, suggesting a slow rising right ventricular pressure pulse; 3 of these patients also had late tricuspid valve closure but the tricuspid component of the first sound was absent. Late onset of pressure rise is thought to result from block in the main right bundle-branch, and a slow rising pulse from block in the distal Purkinje network. These findings explain the conflicting results in previous studies of the first heart sound and right ventricular pressure pulse in patients with right bundle-branch block, and may have prognostic significance.
对20例完全性右束支传导阻滞患者和67例正常受试者,同步记录二尖瓣、三尖瓣和肺动脉瓣的高速超声心动图、心电图和心音图。所有患者均发现肺动脉瓣延迟开放,提示右心室射血延迟。在8例第一心音宽分裂患者中,延迟射血主要与三尖瓣关闭延迟有关,提示右心室压力脉冲起始延迟。在10例第一心音单一的患者中,延迟射血与三尖瓣关闭至肺动脉瓣开放的间隔时间延长有关,提示右心室压力脉冲上升缓慢;其中3例患者三尖瓣关闭也延迟,但第一心音的三尖瓣成分消失。压力上升延迟被认为是由于右束支主干阻滞所致,而脉冲上升缓慢是由于远端浦肯野网络阻滞所致。这些发现解释了先前关于右束支传导阻滞患者第一心音和右心室压力脉冲的研究中相互矛盾的结果,可能具有预后意义。