兔实验性后巩膜穿通性眼外伤。I. 制作方法及自然病程。
Experimental posterior penetrating eye injury in the rabbit. I. Method of production and natural history.
作者信息
Cleary P E, Ryan S J
出版信息
Br J Ophthalmol. 1979 May;63(5):306-11. doi: 10.1136/bjo.63.5.306.
Abstract
A technique has been developed which produces an experimental posterior penetrating eye injury that reproducibly results in traction retinal detachment in rabbit eyes. The standard injury is an incision through the pars plana with vitreous prolapse and incarceration; the wound is then carefully closed with microsurgical techniques. It appears that blood in the vitreous is an essential factor in the development of vitreous traction and of traction retinal detachment. The model, which has been successfully transferred to Rhesus monkey eyes, is considered useful for further histological, electromicroscopical, electrophysiological, and ultrasound studies of posterior penetrating injuries of the eye. Our immediate goal is to assess in a controlled experiment whether pars plana vitrectomy can interrupt the sequence of events leading to traction retinal detachment after a posterior penetrating injury.
摘要
已开发出一种技术，可造成实验性的后部穿透性眼外伤，这种外伤能在兔眼中可重复地导致牵引性视网膜脱离。标准损伤是通过睫状体扁平部切口并伴有玻璃体脱出和嵌顿；然后用显微外科技术小心地缝合伤口。玻璃体中的血液似乎是玻璃体牵引和牵引性视网膜脱离发展过程中的一个关键因素。该模型已成功应用于恒河猴眼，被认为有助于对眼后部穿透性损伤进行进一步的组织学、电子显微镜、电生理学和超声研究。我们当前的目标是在一项对照实验中评估睫状体扁平部玻璃体切除术是否能够中断后部穿透性损伤后导致牵引性视网膜脱离的一系列事件。
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