Leaver P K, Grey R H, Garner A
Br J Ophthalmol. 1979 May;63(5):361-7. doi: 10.1136/bjo.63.5.361.
Long-term assessment of eyes in which silicone oil injection had been used in the treatment of retinal detachment with massive preretinal retraction was undertaken in 92 consecutive patients. While a high incidence of complications, particularly cataract, was confirmed, this study showed that they were probably caused not by any toxic effect of silicone oil but by obstruction of normal metabolic exchange at the silicone-tissue interface. The incidence of complications causing deterioration of vision or serious symptoms was not found to be high, and navigating vision was well preserved.
对92例连续接受硅油注射治疗伴有大量视网膜前膜收缩的视网膜脱离患者的眼睛进行了长期评估。虽然证实并发症发生率很高，尤其是白内障，但这项研究表明，它们可能不是由硅油的任何毒性作用引起的，而是由硅油与组织界面处正常代谢交换受阻所致。导致视力恶化或出现严重症状的并发症发生率并不高，且中心视力得到了良好的保留。
