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霍乱弧菌L型的实验性口服免疫

Experimental oral immunization with L-forms of Vibrio cholerae.

作者信息

Agarwal S C, Ganguly N K

出版信息

Infect Immun. 1972 Jan;5(1):31-4. doi: 10.1128/iai.5.1.31-34.1972.

Abstract

It has been found that oral administration of lysates of L-forms of Vibrio cholerae are antigenic and capable of eliciting an early and high coproantibody response. The L-forms of V. cholerae did not produce any booster effect. Coproantibody rise persists to significant levels even six weeks after oral immunization. L-form lysates of V. cholerae also produce a considerable rise of circulating antibodies and these persist in significantly high titers up to six weeks.

摘要

已发现口服霍乱弧菌L型菌的裂解物具有抗原性,能够引发早期且强烈的粪便抗体反应。霍乱弧菌L型菌未产生任何加强效应。即使在口服免疫六周后,粪便抗体水平仍持续显著升高。霍乱弧菌L型菌裂解物还会使循环抗体显著升高,且这些抗体在高达六周的时间内一直保持在显著的高滴度水平。

相似文献

2
Oral immunization with L-forms of Vibrio cholerae in human volunteers.
Infect Immun. 1972 Jul;6(1):17-20. doi: 10.1128/iai.6.1.17-20.1972.

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