Mantero E
Minerva Med. 1975 Feb 3;66(8):399-404.
The discovery that Hodgkin's disease has a unicentric onset has enabled its prognosis to be modified. In its initial, uniregional stage, in fact, it can be cured by radiotherapy. A satisfactory result will only be obtained, however, if certain fundamental rules are followed: aggressive treatment with extensive radiation fields, radiation of adjacent lymphatic districts, prior splenectomy where necessary.