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颈动脉内膜切除术的发病率。

The morbidity of carotid endarterectomy.

作者信息

Bouchier-Hayes D, De Costa A, MacGowan W A

出版信息

Br J Surg. 1979 Jun;66(6):433-7. doi: 10.1002/bjs.1800660620.

Abstract

The results of 72 carotid endarterectomy operations carried out by three consultant surgeons were analysed. Thirty-eight operations (32.8 per cent) were performed in patients with mild or resolving stroke and 33 operations (45.9 per cent) in patients with transient ischaemic attacks and/or amaurosis fugax. Five patients (7 per cent) died in the early postoperative period, 2 as a result of strokes and the others from cardiac causes. Seventy-six per cent of patients had a satisfactory long term result, remaining free from storke, blindness or recurrent transient ischaemic attacks over the follow-up period of 1--7 years. There were 10 patients (13.8 per cent), including 2 who died, who developed early postoperative neurological deficits; 4 (5.5 per cent) had transient defects and 6 (8.3 per cent) had permanent deficits. Of these patients, 4 had proved occlusions of the reconstructed artery. In 3 patients, cerebral embolization during operation was suspected as the cause. There were, in addition, 2 asymptomatic patients whose reconstruction was shown to be occluded on follow-up postoperative angiography. The continued absence of symptoms, therefore, is no guarantee that the reconstruction is patent and some more objective method of assessment is necessary if the results of carotid endarterectomy are to be critically analysed. The incidence of neurological deficits could, it is believed, be reduced by greater experience with the operation, the routine use of peroperative intra-arterial shunting and peroperative angiography to confirm the patency of the reconstruction.

摘要

对三位顾问外科医生实施的72例颈动脉内膜切除术的结果进行了分析。38例手术(32.8%)是在轻度或正在好转的中风患者中进行的,33例手术(45.9%)是在短暂性脑缺血发作和/或一过性黑矇患者中进行的。5例患者(7%)在术后早期死亡,2例死于中风,其他死于心脏原因。76%的患者获得了满意的长期结果,在1至7年的随访期内未发生中风、失明或复发性短暂性脑缺血发作。有10例患者(13.8%),包括2例死亡患者,出现了术后早期神经功能缺损;4例(5.5%)有短暂性缺损,6例(8.3%)有永久性缺损。在这些患者中,4例证实重建动脉闭塞。3例患者术中怀疑脑栓塞是病因。此外,2例无症状患者术后随访血管造影显示重建血管闭塞。因此,持续无症状并不能保证重建血管通畅,如果要对颈动脉内膜切除术的结果进行严格分析,需要一些更客观的评估方法。据信,通过增加手术经验、常规使用术中动脉内分流术以及术中血管造影以确认重建血管的通畅性,可以降低神经功能缺损的发生率。

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