Trapnell J E
Br J Surg. 1979 Jul;66(7):471-5. doi: 10.1002/bjs.1800660706.
A collected series of 64 cases of chronic relapsing pancreatitis is reported. Analysis of this material reveals several points of interest. There is a difference in the aetiological spectrum in Britain when compared with reports from France and the United States. In particular, nearly half the British cases were idiopathic. The clinical presentation and the age and sex ratios also varied with aetiology. Endoscopic retrograde cannulation of the pancreatic duct was of little value in confirming a diagnosis of pancreatitis in the problem case. This investigation did, however, demonstrate that a widespread dilatation of the pancreatic duct was a minority finding. In those patients with alcoholic pancreatitis follow-up studies have shown that, if the addiction can be broken, there is a 75 per cent chance that pain will diminish or disappear with the passage of time. The main indication for surgical intervention was severe pain and this study has shown that if strict criteria are observed, a worthwhile relief of symptoms can be achieved. In particular, subtotal pancreatectomy produced good results in up to 85 per cent of cases, although with an appreciable short term postoperative morbidity.
本文报告了一组64例慢性复发性胰腺炎病例。对这些病例资料的分析揭示了几个有趣的要点。与法国和美国的报告相比,英国的病因谱有所不同。特别是,近一半的英国病例病因不明。临床表现以及年龄和性别比例也因病因不同而有所差异。在疑难病例中,内镜逆行胰管插管对确诊胰腺炎价值不大。然而,这项检查确实表明胰管广泛扩张只是少数情况。对酒精性胰腺炎患者的随访研究表明,如果能够戒除酒瘾,随着时间推移,75%的患者疼痛会减轻或消失。手术干预的主要指征是严重疼痛,本研究表明,如果遵循严格标准,症状可得到有效缓解。特别是,胰次全切除术在高达85%的病例中取得了良好效果,尽管术后短期内有明显的发病率。