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梅毒兔卫星淋巴结的超微结构研究

Ultrastructural study of satellite lymph nodes in syphilitic rabbits.

作者信息

Lapushin R W, Baughn R E, Musher D M, Gyorkey P

出版信息

Br J Vener Dis. 1979 Jun;55(3):168-72. doi: 10.1136/sti.55.3.168.

DOI:10.1136/sti.55.3.168
PMID:466381
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1045622/
Abstract

In an electron microscopy study of lymph nodes from syphilitic rabbits plasmablasts and plasma cells were unequivocally identified in germinal centres. Up to 20% of the plasma cells possessed unusual cytological features. Paracortical hypoplasia was shown to be associated with actively phagocytic histiocytes. These findings may reflect morphological correlates of the aberrant immune regulation which has been observed in infection with Treponema pallidum.

摘要

在一项对梅毒兔淋巴结的电子显微镜研究中,在生发中心明确鉴定出了成浆细胞和浆细胞。高达20%的浆细胞具有异常的细胞学特征。副皮质发育不全被证明与活跃吞噬的组织细胞有关。这些发现可能反映了在梅毒螺旋体感染中观察到的异常免疫调节的形态学关联。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2985/1045622/1dc171a1fa96/brjvendis00033-0011-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2985/1045622/7bb3d19621d7/brjvendis00033-0009-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2985/1045622/c34c9828bf50/brjvendis00033-0010-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2985/1045622/6a1d190b4faf/brjvendis00033-0010-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2985/1045622/13409dc3f04a/brjvendis00033-0010-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2985/1045622/3a95084f5169/brjvendis00033-0011-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2985/1045622/1dc171a1fa96/brjvendis00033-0011-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2985/1045622/7bb3d19621d7/brjvendis00033-0009-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2985/1045622/c34c9828bf50/brjvendis00033-0010-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2985/1045622/6a1d190b4faf/brjvendis00033-0010-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2985/1045622/13409dc3f04a/brjvendis00033-0010-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2985/1045622/3a95084f5169/brjvendis00033-0011-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2985/1045622/1dc171a1fa96/brjvendis00033-0011-b.jpg

相似文献

1
Ultrastructural study of satellite lymph nodes in syphilitic rabbits.梅毒兔卫星淋巴结的超微结构研究
Br J Vener Dis. 1979 Jun;55(3):168-72. doi: 10.1136/sti.55.3.168.
2
The electron microscopic features of sinus histiocytosis with massive lymphadenopathy: a study of 11 cases.巨大淋巴结病伴窦性组织细胞增多症的电子显微镜特征:11例研究
Ultrastruct Pathol. 1981 Apr-Jun;2(2):101-19. doi: 10.3109/01913128109064239.
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[Dynamics of mast and plasma cell distribution in the lymph nodes of a mouse infected with a pathogenic strain of Treponema pallidum].[感染梅毒螺旋体致病菌株的小鼠淋巴结中肥大细胞和浆细胞分布的动态变化]
Vestn Dermatol Venerol. 1979 Dec(12):13-6.
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[The immunoblastic lymphadenopathy. Histological, cytological and ultrastructural findings (author's transl)].免疫母细胞性淋巴结病。组织学、细胞学及超微结构检查结果(作者译)
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Diagnostic pitfalls in pathological diagnosis of infectious disease: patients with syphilitic lymphadenitis often present with inconspicuous history of infection.传染病病理诊断中的诊断陷阱:梅毒淋巴结炎患者通常感染史不明显。
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Malignant histiocytosis. Ultrastructural and immunocytochemical characterization.恶性组织细胞增多症。超微结构及免疫细胞化学特征
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Experimental syphilitic orchitis in rabbits: ultrastructural appearance of Treponema pallidum during phagocytosis and dissolution by macrophages in vivo.兔实验性梅毒性睾丸炎:梅毒螺旋体在体内被巨噬细胞吞噬和溶解过程中的超微结构表现
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[Clinical laboratory and electron microscopic study of the cell makeup of the lymph nodes of white mice infected with different Treponema pallidum strains].[感染不同梅毒螺旋体菌株的小白鼠淋巴结细胞组成的临床实验室及电子显微镜研究]
Vestn Dermatol Venerol. 1981 Jul(7):21-4.
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Malignant histiocytosis: a histological and ultrastructural study of lymph nodes in six cases.恶性组织细胞增多症:6例淋巴结的组织学和超微结构研究
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An ultrastructural study of subacute necrotizing lymphadenitis.
Am J Pathol. 1982 Jun;107(3):292-9.

本文引用的文献

1
The use of lead citrate at high pH as an electron-opaque stain in electron microscopy.在电子显微镜检查中,将高pH值的柠檬酸铅用作电子不透明染色剂。
J Cell Biol. 1963 Apr;17(1):208-12. doi: 10.1083/jcb.17.1.208.
2
Embedding in epoxy resins for ultrathin sectioning in electron microscopy.嵌入环氧树脂用于电子显微镜超薄切片。
Stain Technol. 1960 Nov;35:313-23. doi: 10.3109/10520296009114754.
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Cell-mediated immunity and lymphocyte transformation in syphilis.梅毒中的细胞介导免疫与淋巴细胞转化
Proc R Soc Med. 1971 Apr;64(4):426-8. doi: 10.1177/003591577106400440.
4
Luetic lymphadenitis: a clinical and histologic study of 20 cases.梅毒性淋巴结炎:20例临床与组织学研究
Am J Clin Pathol. 1970 Mar;53(3):304-14. doi: 10.1093/ajcp/53.3.304.
5
Runting syndrome in neonatal rabbits infected with Treponema pallidum.感染梅毒螺旋体的新生兔发育迟缓综合征
Clin Exp Immunol. 1967 May;2(3):311-20.
6
In vitro lymphocyte response to Treponema refringens im human syphilis.人梅毒中对致密螺旋体的体外淋巴细胞反应。
Infect Immun. 1974 Apr;9(4):654-7. doi: 10.1128/iai.9.4.654-657.1974.
7
Why is the infectious stage of syphilis prolonged?梅毒的传染期为何会延长?
Br J Vener Dis. 1974 Feb;50(1):45-9. doi: 10.1136/sti.50.1.45.
8
Reduced lymphocyte transformation due to a plasma factor in patients with active syphilis.活动性梅毒患者血浆因子导致淋巴细胞转化降低。
Lancet. 1969 Aug 2;2(7614):246-7. doi: 10.1016/s0140-6736(69)90010-5.
9
Lymphocyte transformation in syphilis: an in vitro correlate of immune suppression in vivo?梅毒中的淋巴细胞转化:体内免疫抑制的体外相关因素?
Infect Immun. 1975 Jun;11(6):1261-4. doi: 10.1128/iai.11.6.1261-1264.1975.
10
Plasma cell immunoglobulin secretion: arrest is accompanied by alterations of the golgi complex.浆细胞免疫球蛋白分泌:停滞伴随着高尔基体复合体的改变。
J Exp Med. 1977 Nov 1;146(5):1332-45. doi: 10.1084/jem.146.5.1332.