利兹关于高压氧放疗对头颈部癌治疗效果的研究结果。
The Leeds results for radiotherapy in HBO for carcinoma of the head and neck.
作者信息
Berry G H, Dixon B, Ward A J
出版信息
Clin Radiol. 1979 Sep;30(5):591-2. doi: 10.1016/s0009-9260(79)80207-x.
PMID:466964
Abstract
Follow-up data at five years are reported for 24 patients with squamous cell carcinoma of the head and neck, included in a randomised prospective MRC study of radiotherapy in hyperbaric oxygen (10 fractions) or air (15 or 20 fractions). Although few, the data show a significant gain in local control (P less than 0.001) and survival (P less than 0.05) with the use of hyperbaric oxygen but no increased tissue reactions or morbidity.
摘要
在一项随机前瞻性医学研究委员会（MRC）关于高压氧（10次分割）或空气（15或20次分割）放疗对头颈部鳞状细胞癌疗效的研究中，报告了24例患者的五年随访数据。尽管数据量少，但结果显示使用高压氧可显著提高局部控制率（P<0.001）和生存率（P<0.05），且未增加组织反应或发病率。
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