去除外细胞壁层对革兰氏阴性细菌放线菌素敏感性的影响。
Effect of the removal of outer cell wall layers on the actinomycin susceptibility of a gram-negative bacterium.
作者信息
MacAlister T J, Costerton J W, Cheng K J
出版信息
Antimicrob Agents Chemother. 1972 May;1(5):447-9. doi: 10.1128/AAC.1.5.447.
Abstract
Removal of the outer cell wall layers of a gram-negative marine pseudomonad (B-16) showed that these cells are penetrable by actinomycin D and that, therefore, neither the cytoplasmic membrane nor the peptidoglycan layer constitutes the barrier which excludes this antibiotic from intact cells, but that this barrier is formed by the outer layers of the cell wall which include the lipopolysaccharide component and the double-track layer.
摘要
去除革兰氏阴性海洋假单胞菌（B - 16）的外层细胞壁后发现，这些细胞可被放线菌素D穿透，因此，细胞质膜和肽聚糖层均不构成将这种抗生素排除在完整细胞之外的屏障，而这种屏障是由包括脂多糖成分和双轨层的细胞壁外层形成的。
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