Carr J, Carr I, Dreher B, Franks C R
Experientia. 1979 Jun 15;35(6):825-7. doi: 10.1007/BF01968276.
A model of lymphatic metastasis established by injecting Walker rat carcinoma cells into the rat footpad was used to study the output of tumour cells from the footpad. The lymphatic efferent from the footpad was cannulated in a group of rats with advanced neoplasm; it was shown that the output of tumour cells was continuous over periods up to 90 min and ranged from 10(2)-10(5) cells/min.
通过将沃克大鼠癌细胞注入大鼠足垫建立的淋巴转移模型，用于研究足垫中肿瘤细胞的输出情况。在一组患有晚期肿瘤的大鼠中，将足垫的淋巴输出管插管；结果显示，肿瘤细胞的输出在长达90分钟的时间段内持续存在，输出范围为每分钟10² - 10⁵个细胞。
