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慢性透析患者的血清补体与蛋白质代谢

Serum complement and protein metabolism in chronic dialysis patients.

作者信息

Falkenhagen D, Falkenhagen U, Schmicker R, Tessenow W, Holtz M, Schmidt R, Schmitt E, Klinkmann H

出版信息

Int J Artif Organs. 1979 Mar;2(2):65-8.

PMID:468396
Abstract
  1. Patients receiving regular hemodialysis treatment who are permitted to select their own diets are in danger of a protein deficiency manifested by a significant reduction in serum transferrin and in complement C3c. 2. Correlation analysis within the dialysis group revealed no secure connexion between the complement C3c and total hemolytic activity respectively, and transferrin levels. 3. Analysis of diets showed that protein intake and the serum transferrin level correlate. No such correlation was found for the complement C3c or total hemolytic activity. 4. Low transferrin levels in the serum appear to result in more severe anemia among dialysis patients. 5. Knowledge of the serum transferrin level permits much more exact assessment of the protein metabolism in regular hemodialysis patients than knowledge of the total hemolytic activity or the level of the complement C3c.
摘要
  1. 接受定期血液透析治疗且被允许自行选择饮食的患者,有出现蛋白质缺乏的风险,表现为血清转铁蛋白和补体C3c显著降低。2. 透析组内的相关性分析显示,补体C3c与总溶血活性之间以及转铁蛋白水平之间均无可靠联系。3. 饮食分析表明,蛋白质摄入量与血清转铁蛋白水平相关。补体C3c或总溶血活性则未发现此类相关性。4. 血清转铁蛋白水平低似乎会导致透析患者出现更严重的贫血。5. 与了解总溶血活性或补体C3c水平相比,了解血清转铁蛋白水平能更准确地评估定期血液透析患者的蛋白质代谢情况。

相似文献

1
Serum complement and protein metabolism in chronic dialysis patients.慢性透析患者的血清补体与蛋白质代谢
Int J Artif Organs. 1979 Mar;2(2):65-8.
2
[Serum complement and protein metabolism in chronic dialysis patients].[慢性透析患者的血清补体与蛋白质代谢]
Z Urol Nephrol. 1979 Feb;72(2):89-96.
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Plasma amino acids and protein levels in chronic renal failure and changes caused by oral supplements of essential amino acids.慢性肾功能衰竭患者的血浆氨基酸和蛋白质水平以及口服必需氨基酸补充剂所引起的变化。
Clin Chim Acta. 1975 Jun 2;61(2):205-13. doi: 10.1016/0009-8981(75)90316-2.
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[The influence of l-histidine substitution on protein metabolism (transferrin and complement system) and renal anaemia in endstage renal failure (author's transl)].
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[Serum transferrin levels in chronic renal failure. 1. Serum transferrin levels in patients under hemodialysis, with special reference to its relationship with food intake].[慢性肾衰竭患者的血清转铁蛋白水平。1. 血液透析患者的血清转铁蛋白水平,特别提及与食物摄入量的关系]
Nihon Jinzo Gakkai Shi. 1976 Apr;18(4):281-91.
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[The effect of hemodialysis with frequent use of cuprophan and polysulfone membranes on activation of complement in patients with chronic renal failure].[频繁使用铜仿膜和聚砜膜进行血液透析对慢性肾衰竭患者补体激活的影响]
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Serum proteins as indicators of poor dietary intake in patients with chronic renal failure.血清蛋白作为慢性肾衰竭患者饮食摄入不良的指标。
Clin Nephrol. 1975;3(3):114-8.
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[Serum transferrin in chronic kidney failure with conservative treatment and hemodialysis].[保守治疗及血液透析的慢性肾衰竭患者血清转铁蛋白]
Z Urol Nephrol. 1978 Jan;71(1):13-20.
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[Evaluation of protein balance in patients with chronic kidney insufficiency and in hemodialysis patients].[慢性肾功能不全患者及血液透析患者蛋白质平衡的评估]
Z Urol Nephrol. 1976 Dec;69(12):911-99.
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Rapid elevation of transferrin saturation and serum hepcidin concentration in hemodialysis patients after intravenous iron infusion.静脉注射铁剂后血液透析患者转铁蛋白饱和度和血清铁调素浓度迅速升高。
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