[慢性透析患者的血清补体与蛋白质代谢]

[Serum complement and protein metabolism in chronic dialysis patients].

Falkenhagen D, Falkenhagen U, Schmicker R, Tessenow W, Holtz M, Schmidt R, Schmitt E

Z Urol Nephrol. 1979 Feb;72(2):89-96.

Abstract

When a so-called free diet is granted there is the danger of a protein deficit, which can be proved in a significant decrease of the serum transferrin and of the complement factor E3c, in patients in the chronic haemodialysis programme. 2. Within the group undergoing dialysis a correlation analysis did not result in a statistically ascertained connection between the complement factor C3c and the total haemolytic activity and the transferrin, respectively. 3. On the basis of a diet analysis a connection between the protein supply and the serum transferrin level could be established, which was not to be proved for the complement factor C3c and the total haemolytic activity, respectively. 4. Low transferrin values in the serum seem to be followed by a deterioration of the anaemia situation of the patient undergoing haemodialysis. 5. Compared with the total haemolytic activity and the complement factor C3c the determination of the serum transferrin allows an essentially exacter information about the protein metabolism of the patient undergoing a chronic haemodialysis.

摘要

当给予所谓的自由饮食时，存在蛋白质缺乏的风险，这在慢性血液透析项目患者中可通过血清转铁蛋白和补体因子E3c的显著降低得到证实。2. 在透析组中，相关性分析未得出补体因子C3c与总溶血活性及转铁蛋白之间具有统计学意义的关联。3. 根据饮食分析，可确定蛋白质供应与血清转铁蛋白水平之间的联系，但补体因子C3c与总溶血活性之间不存在这种联系。4. 血清中转铁蛋白值较低似乎会导致血液透析患者贫血状况恶化。5. 与总溶血活性和补体因子C3c相比，血清转铁蛋白的测定能更准确地反映慢性血液透析患者的蛋白质代谢情况。