Ticho U, Cohen T, Brautbar C
Isr J Med Sci. 1979 Feb;15(2):124-7.
HLA antigens of the A and B loci were determined in 57 Israeli patients with primary open angle glaucoma (POAG) presenting visual field loss and in 715 normal control subjects. The glaucoma patients and control subjects were non-related and randomly selected from the Jewish Israeli population. Frequencies of HLA antigens among the POAG patients showed no differences from those observed in the control subjects. Similar results were observed for all patients as well as within subgroups of the patient population as defined by origin. Thus, the association reported between B7 and/or B12 and POAG in white and black Americans could not be confirmed in an Israeli population.
对57例出现视野缺损的以色列原发性开角型青光眼（POAG）患者以及715名正常对照者进行了A和B位点的HLA抗原检测。青光眼患者和对照者无亲缘关系，均从以色列犹太人群体中随机选取。POAG患者中HLA抗原的频率与对照者中观察到的频率无差异。所有患者以及按来源定义的患者亚组均观察到类似结果。因此，在美国白人和黑人中报道的B7和/或B12与POAG之间的关联在以色列人群中无法得到证实。
