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通过高效液相色谱法分离肽类抗生素、蜡状菌素和十三肽菌素(芽孢杆菌属抗生素研究。XXVI)

Resolution of peptide antibiotics, cerexins and tridecaptins, by high performance liquid chromatography (studies on antibiotics from the genus Bacillus. XXVI).

作者信息

Shoji J, Kato T, Terabe S, Konaka R

出版信息

J Antibiot (Tokyo). 1979 Apr;32(4):313-9. doi: 10.7164/antibiotics.32.313.

Abstract

By high performance liquid chromatography, cerexin B was separated into four components (B1, B2, B3 and B4), cerexin D into four components (D1, D2, D3 and D4), tridecaptin A into components (A alpha and A beta), tridecaptin B into four components (B alpha, B beta, B gamma and B delta) and tridecaptin C into three components (C alpha 1, C alpha 2 and C beta 1). All components were preparatively isolated, and their fatty acid and amino acid compositions determined for structural elucidation.

摘要

通过高效液相色谱法,将cerexin B分离为四个组分(B1、B2、B3和B4),将cerexin D分离为四个组分(D1、D2、D3和D4),将tridecaptin A分离为两个组分(Aα和Aβ),将tridecaptin B分离为四个组分(Bα、Bβ、Bγ和Bδ),并将tridecaptin C分离为三个组分(Cα1、Cα2和Cβ1)。所有组分均通过制备方法进行分离,并测定其脂肪酸和氨基酸组成以进行结构解析。

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