培养的单个交感神经元的分支模式。
Branching patterns of individual sympathetic neurons in culture.
作者信息
Bray D
出版信息
J Cell Biol. 1973 Mar;56(3):702-12. doi: 10.1083/jcb.56.3.702.
Abstract
The growth of single sympathetic neurons in tissue culture was examined with particular regard to the way in which the patterns of axonal or dendritic processes (here called nerve fibers), were formed. The tips of the fibers were seen to advance in straight lines and to grow at rates that did not vary appreciably with time, with their position in the cell outgrowth, or with the fiber diameter. Most of the branch points were formed by the bifurcation of a fiber tip (growth cone), apparently at random, and thereafter remained at about the same distance from the cell body. It seemed that the final shape of a neuron was the result of the reiterated and largely autonomous activities of the growth cones. The other parts of the cell played a supportive role but, apart from this, had no obvious influence on the final pattern of branches formed.
摘要
在组织培养中研究了单个交感神经元的生长情况，特别关注轴突或树突状突起（此处称为神经纤维）模式的形成方式。可以看到纤维末端呈直线前进，并且以不随时间、细胞突起中的位置或纤维直径而明显变化的速率生长。大多数分支点是由纤维末端（生长锥）的分叉形成的，显然是随机的，此后它们与细胞体的距离大致保持不变。似乎神经元的最终形状是生长锥反复进行且基本自主活动的结果。细胞的其他部分起到支持作用，但除此之外，对最终形成的分支模式没有明显影响。
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