Griffiths I R
J Neurol Neurosurg Psychiatry. 1973 Feb;36(1):42-9. doi: 10.1136/jnnp.36.1.42.
The effect of CO(2) on the spinal cord blood flow was investigated in nine dogs. The flow was closely correlated with the paCO(2) and at about 85 mmHg was double the normocarbic flow. The effect of pO(2) was studied in a further nine dogs. Hypoxia markedly increased the flow which was maximal at paO(2) 30-40 mmHg. The vasoconstrictor effect of hypocarbia was absent or decreased in hypoxia. The response of the cord vessels to the blood gases was very similar to that of the brain.
在9只狗身上研究了二氧化碳对脊髓血流的影响。血流与动脉血二氧化碳分压密切相关,在约85 mmHg时是正常碳酸血症时血流的两倍。在另外9只狗身上研究了氧分压的影响。低氧显著增加血流,在动脉血氧分压30 - 40 mmHg时达到最大值。在低氧状态下,低碳酸血症的血管收缩作用消失或减弱。脊髓血管对血气的反应与脑的反应非常相似。