Dubuisson J B, Barbot J, Henrion R
J Gynecol Obstet Biol Reprod (Paris). 1979 Jan-Feb;8(1):39-41.
Prenatal diagnosis based on anatomic definition of the fetus in utero is an difficult task, in the first trimester of pregnancy. The authors have recently introduced a new method : contact embryoscopy which consist in applying the optic piece of a contact hysteroscope (diameter of six millemeters) to the intact and translucent ovular membranes by the cervix. They have performed fifty embryoscopy prior to termination of pregnancy at 8 to 12 weeks. In 41 cases, they have seen the hands of fetus with the fingers. If this technic fails, it is possible, later, to use Echography and fetoscopy. The side-effects are discussed. Contact embryoscopy would be particularly useful in the detection of malformations of the extremities, for instance : chondro-ectodermal dysplasia (Ellis Van Creveld Syndrome) or ectrodactily.
在妊娠早期,基于子宫内胎儿的解剖学定义进行产前诊断是一项艰巨的任务。作者最近引入了一种新方法:接触式胚胎镜检查,即通过宫颈将接触式宫腔镜(直径6毫米)的目镜应用于完整且半透明的卵膜。他们在妊娠8至12周终止妊娠前进行了50次胚胎镜检查。在41例病例中,他们看到了胎儿带有手指的手。如果该技术失败,之后可以使用超声检查和胎儿镜检查。文中讨论了副作用。接触式胚胎镜检查在检测肢体畸形方面可能特别有用,例如:软骨外胚层发育不良(埃利斯-范克里维尔德综合征)或缺指(趾)畸形。