非洲胰岛素分泌不足型糖尿病
Insulinopenic diabetes in Africa.
作者信息
Wicks A C, Jones J J
出版信息
Br Med J. 1973 Mar 31;1(5856):773-8. doi: 10.1136/bmj.1.5856.773.
Abstract
The high proportion of unrefined carbohydrates (maize meal) in the diet of Africans could be responsible for their low insulin secretion. The consequent insulinopenia in the general African population may explain the comparative rarity of typical non-insulin dependent diabetes mellitus, and also the virtual absence of coronary heart disease. Changes in growth hormone secretion and in serum lipids, known to be associated with diabetes in Europeans, are also found in African patients.
摘要
非洲人饮食中未精制碳水化合物（玉米粉）的高比例可能是其胰岛素分泌量低的原因。非洲普通人群中随之而来的胰岛素缺乏症可能解释了典型的非胰岛素依赖型糖尿病相对罕见的原因，以及冠心病实际上不存在的原因。在非洲患者中也发现了生长激素分泌和血脂的变化，而这些变化在欧洲人身上已知与糖尿病有关。
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