胆固醇胆结石患者胆汁的胆固醇及胆盐研究
Cholesterol and bile salt studies on the bile of patients with cholesterol gallstones.
作者信息
Heller F, Bouchier I A
出版信息
Gut. 1973 Feb;14(2):83-8. doi: 10.1136/gut.14.2.83.
Abstract
Gallbladder bile from patients with cholesterol stones and control patients without cholesterol stones was analysed for the relative concentrations of bile salts, phospholipids, and cholesterol. It was not possible to distinguish stone-forming from control biles when these were plotted on triangular coordinates. There was a significant increase in the dihydroxy: trihydroxy bile salt ratio in the patients with cholesterol gallstones. The maximum cholesterol holding capacity for the bile salts was determined and no difference could be detected in the ability of the bile salts from either cholesterol stone-containing and control bile samples to dissolve cholesterol.
摘要
对患有胆固醇结石的患者以及无胆固醇结石的对照患者的胆囊胆汁进行分析，以测定胆汁盐、磷脂和胆固醇的相对浓度。当将这些胆汁绘制在三角坐标上时，无法区分形成结石的胆汁和对照胆汁。胆固醇胆结石患者的二羟基：三羟基胆汁盐比例显著增加。测定了胆汁盐的最大胆固醇容纳量，未检测到含胆固醇结石的胆汁样本和对照胆汁样本中的胆汁盐溶解胆固醇能力的差异。
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