Rowe R W
J Cell Biol. 1973 May;57(2):261-77. doi: 10.1083/jcb.57.2.261.
The Z disk ultrastructure of white, intermediate, and red fibers from mammalian muscle is examined. Three models are proposed that explain the differences between the three types of Z disk. The three models are all based on the same concept, i.e., looping filaments from both sides of the Z disk. The differences between the models are in terms of the spatial relationships of adjacent loops within the Z disk. In the white fiber Z disk model all the loops from one side of the Z disk are on the same plane. In intermediate fibers there are two planes of loops from both sides of the Z disk, whereas in red fibers there are three planes of loops from both sides. The implications of these three structures are discussed in relation to known physiological differences between the fiber types.
对哺乳动物肌肉中白色、中间型和红色肌纤维的Z盘超微结构进行了研究。提出了三种模型来解释三种类型Z盘之间的差异。这三种模型都基于相同的概念,即Z盘两侧的环状细丝。模型之间的差异在于Z盘内相邻环的空间关系。在白色肌纤维Z盘模型中,Z盘一侧的所有环都在同一平面上。在中间型肌纤维中,Z盘两侧有两个环平面,而在红色肌纤维中,两侧有三个环平面。结合已知的纤维类型间生理差异,讨论了这三种结构的意义。