Therapeutic and toxic effects observed with different dosage programs of cyclophosphamide in treatment of steroid-responsive but frequently relapsing nephrotic syndrome.

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作者信息

McCrory W W, Shibuya M, Lu W H, Lewy J E

出版信息

J Pediatr. 1973 Apr;82(4):614-8. doi: 10.1016/s0022-3476(73)80586-4.

DOI:10.1016/s0022-3476(73)80586-4

PMID:4698338

Abstract

摘要

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Therapeutic and toxic effects observed with different dosage programs of cyclophosphamide in treatment of steroid-responsive but frequently relapsing nephrotic syndrome.

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A controlled prospective study of cyclophosphamide in relapsing, corticosteroid-responsive, minimal-lesion nephrotic syndrome in childhood.

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Cytostatic treatment of nephrotic syndrome in children.儿童肾病综合征的细胞毒性治疗。

Acta Paediatr Acad Sci Hung. 1970;11(3):263-76.

Cyclophosphamide treatment in steroid-sensitive nephrotic syndrome of childhood.

Lancet. 1975 Jan 11;1(7898):55-8. doi: 10.1016/s0140-6736(75)91068-5.

Prospective, controlled trial of cyclophosphamide therapy in children with nephrotic syndrome. Report of the International study of Kidney Disease in Children.环磷酰胺治疗儿童肾病综合征的前瞻性对照试验。儿童肾脏病国际研究报告。

Lancet. 1974 Aug 24;2(7878):423-7.

Long-term assessment of cyclophosphamide therapy for nephrosis in children.

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How to manage a child with steroid-responsive nephrotic syndrome when dose of prednisolone is reduced or when placed on high-dose alternate day steroids.当泼尼松龙剂量减少或采用大剂量隔日服用类固醇时，如何管理患有类固醇反应性肾病综合征的儿童。

Pediatr Nephrol. 1992 Nov;6(6):522. doi: 10.1007/BF00866490.

Treatment with tacrolimus and prednisolone is preferable to intravenous cyclophosphamide as the initial therapy for children with steroid-resistant nephrotic syndrome.对于激素耐药性肾病综合征患儿，他克莫司和泼尼松龙治疗优于静脉注射环磷酰胺作为初始治疗。

Kidney Int. 2012 Nov;82(10):1130-5. doi: 10.1038/ki.2012.238. Epub 2012 Jul 4.

Long-term stability of remission in nephrotic syndrome after treatment with cyclophosphamide.环磷酰胺治疗后肾病综合征缓解的长期稳定性

Br Med J. 1974 Oct 5;4(5935):7-11. doi: 10.1136/bmj.4.5935.7.

Comparative trial of 2 weeks and 8 weeks cyclophosphamide in steroid-sensitive relapsing nephrotic syndrome of childhood.儿童激素敏感型复发性肾病综合征中2周与8周环磷酰胺治疗的对比试验

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Non-corticosteroid immunosuppressive medications for steroid-sensitive nephrotic syndrome in children.儿童类固醇敏感型肾病综合征的非皮质类固醇类免疫抑制药物。

Cochrane Database Syst Rev. 2024 Nov 8;11(11):CD002290. doi: 10.1002/14651858.CD002290.pub6.

Non-corticosteroid immunosuppressive medications for steroid-sensitive nephrotic syndrome in children.用于儿童激素敏感型肾病综合征的非皮质类固醇免疫抑制药物。

Cochrane Database Syst Rev. 2020 Apr 16;4(4):CD002290. doi: 10.1002/14651858.CD002290.pub5.

Corticosteroid therapy for nephrotic syndrome in children.儿童肾病综合征的皮质类固醇治疗

Cochrane Database Syst Rev. 2015 Mar 18;2015(3):CD001533. doi: 10.1002/14651858.CD001533.pub5.

Long-term follow-up after cyclophosphamide and cyclosporine-A therapy in steroid-dependent and -resistant nephrotic syndrome.环磷酰胺和环孢素A治疗激素依赖型和激素抵抗型肾病综合征后的长期随访

Pediatr Nephrol. 2008 Jul;23(7):1085-92. doi: 10.1007/s00467-008-0771-8. Epub 2008 Mar 7.

Long-term stability of remission in nephrotic syndrome after treatment with cyclophosphamide.环磷酰胺治疗后肾病综合征缓解的长期稳定性

Br Med J. 1974 Oct 5;4(5935):7-11. doi: 10.1136/bmj.4.5935.7.

Minimal change nephrotic syndrome and cyclophosphamide.微小病变肾病综合征与环磷酰胺

Arch Dis Child. 1986 Aug;61(8):727-9. doi: 10.1136/adc.61.8.727.

Cyclophosphamide in treatment of minimal change nephrotic syndrome.

Eur J Pediatr. 1988 Apr;147(3):239-41. doi: 10.1007/BF00442686.

Eight and 12 week courses of cyclophosphamide in nephrotic syndrome.环磷酰胺治疗肾病综合征的8周和12周疗程。

Arch Dis Child. 1990 Oct;65(10):1147-50. doi: 10.1136/adc.65.10.1147.

Clinical use of immunosuppressive drugs: part II.免疫抑制药物的临床应用：第二部分。

Drugs. 1976;11(2):90-112. doi: 10.2165/00003495-197611020-00002.

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