Schou M, Amdisen A, Steenstrup O R
Br Med J. 1973 Apr 21;2(5859):137-8. doi: 10.1136/bmj.2.5859.137.
The renal lithium clearance of a manic-depressive woman rose when she became pregnant and fell to the prepregnancy level when she gave birth. The lithium clearances of four healthy women were higher during pregnancy than after delivery. This emphasizes the need for frequent determinations of the serum lithium concentration and appropriate dosage adjustments during pregnancy and delivery.
一名躁郁症女性在怀孕时肾脏对锂的清除率升高，分娩后又降至孕前水平。四名健康女性在孕期的锂清除率高于产后。这强调了在孕期和分娩期间需要频繁测定血清锂浓度并进行适当的剂量调整。
