与叶酸缺乏相关的神经系统疾病。
Neurological disease associated with folate deficiency.
作者信息
Reynolds E H, Rothfeld P, Pincus J H
出版信息
Br Med J. 1973 May 19;2(5863):398-400. doi: 10.1136/bmj.2.5863.398.
Abstract
In a general medical hospital population the neurological status of 24 patients with severe folate deficiency was compared with that of a control group of 21 patients with normal serum folate. A significant increase of organic brain syndrome and pyramidal tract damage was found in the folate-deficient group. These findings were independent of the degree of anaemia or the presence of alcoholism. These data are consistent with the view that severe folate deficiency may cause neurological deficits.
摘要
在一家综合医院的患者群体中，对24例严重叶酸缺乏患者的神经状态与21例血清叶酸正常的对照组患者进行了比较。结果发现，叶酸缺乏组的器质性脑综合征和锥体束损害显著增加。这些发现与贫血程度或是否存在酒精中毒无关。这些数据支持严重叶酸缺乏可能导致神经功能缺损这一观点。
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