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Physiologic disposition of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU) and 1-(2-chloroethyl)-3-(4-methyl cyclohexyl)-1-nitrosourea (Me CCNU) in man.

作者信息

Sponzo R W, DeVita V T, Oliverio V T

出版信息

Cancer. 1973 May;31(5):1154-6. doi: 10.1002/1097-0142(197305)31:5<1154::aid-cncr2820310517>3.0.co;2-b.

DOI:10.1002/1097-0142(197305)31:5<1154::aid-cncr2820310517>3.0.co;2-b
PMID:4705152
Abstract
摘要

相似文献

1
Physiologic disposition of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU) and 1-(2-chloroethyl)-3-(4-methyl cyclohexyl)-1-nitrosourea (Me CCNU) in man.1-(2-氯乙基)-3-环己基-1-亚硝基脲(CCNU)和1-(2-氯乙基)-3-(4-甲基环己基)-1-亚硝基脲(Me CCNU)在人体中的生理处置
Cancer. 1973 May;31(5):1154-6. doi: 10.1002/1097-0142(197305)31:5<1154::aid-cncr2820310517>3.0.co;2-b.
2
Initial clinical trials with methyl-CCNU 1-(2-chlorethyl)-3-(4-methyl cyclohexyl)-1-nitrosourea (MeCCNU).
Cancer. 1973 May;31(5):1164-9. doi: 10.1002/1097-0142(197305)31:5<1164::aid-cncr2820310519>3.0.co;2-4.
3
CCNU (1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea, NSC-79037) in the treatment of cancer. Phase II study.环己亚硝脲(1-(2-氯乙基)-3-环己基-1-亚硝基脲,NSC-79037)治疗癌症。II期研究。
Cancer. 1973 Jul;32(1):38-43. doi: 10.1002/1097-0142(197307)32:1<38::aid-cncr2820320105>3.0.co;2-i.
4
Combination chemotherapy with 1-(2-chloroethyl-3-cyclohexyl-1-nitrosourea) (CCNU), vincristine and methotrexate in primary and metastatic brain tumors--a preliminary report.1-(2-氯乙基-3-环己基-1-亚硝基脲)(CCNU)、长春新碱和甲氨蝶呤联合化疗用于原发性和转移性脑肿瘤——初步报告
Eur J Cancer (1965). 1973 Sep;9(9):627-34. doi: 10.1016/0014-2964(73)90004-2.
5
1,-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (methyl CCNU) and adriamycin combination therapy.1, -(2-氯乙基)-3-环己基-1-亚硝基脲(甲基环己亚硝脲)与阿霉素联合治疗。
Cancer. 1974 Nov;34(5):1593-7. doi: 10.1002/1097-0142(197411)34:5<1593::aid-cncr2820340505>3.0.co;2-1.
6
Treatment of brain tumors with 1-(2 chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU).用1-(2-氯乙基)-3-环己基-1-亚硝基脲(CCNU)治疗脑肿瘤。
Nihon Geka Hokan. 1973 Apr;42(2):184-9.
7
[On the therapy of lymphogranuloma. CCNU (1(2-chlorethyl)-3-cyclohexyl-1-nitrosourea) and BCNU (1,3-bis(2-chlorethyl)-1-nitrosourea) as well as BCNU combinations in Hodgkin's lymphogranuloma, stage 3 and 4].
Schweiz Med Wochenschr. 1972 Oct 28;102(43):1546-51.
8
Hydroxylation of the carcinostatic 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU) by rat liver microsomes.大鼠肝脏微粒体对抗癌药物1-(2-氯乙基)-3-环己基-1-亚硝基脲(CCNU)的羟基化作用。
Biochem Biophys Res Commun. 1974 Mar 25;57(2):426-33. doi: 10.1016/0006-291x(74)90948-6.
9
Sequential 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (NSC 79037) and 5-fluorouracil (NSC 19893) therapy of gastrointestinal cancer.胃肠道癌的序贯1-(2-氯乙基)-3-环己基-1-亚硝基脲(NSC 79037)和5-氟尿嘧啶(NSC 19893)治疗
Cancer Res. 1972 Jun;32(6):1280-2.
10
Effects of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU; NSC-79037) and its degradation products on progression of L1210 cells through the cell cycle.
Cancer Chemother Rep. 1971 Jun;55(3):215-20.

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HPLC method validation for the quantification of lomustine to study pharmacokinetics of thermosensitive liposome-encapsulated lomustine containing iohexol for CT imaging in C6 glioma rats.用于定量洛莫司汀的高效液相色谱法验证,以研究含碘海醇的热敏脂质体包裹洛莫司汀在C6胶质瘤大鼠中用于CT成像的药代动力学。
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Distribution of Bratton-Marshall-positive material in mice following intravenous injections of nitrosoureas.静脉注射亚硝基脲后小鼠体内布拉顿 - 马歇尔阳性物质的分布情况。
Cancer Chemother Pharmacol. 1980;4(4):243-8. doi: 10.1007/BF00255268.
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Br J Cancer. 1980 Feb;41(2):189-98. doi: 10.1038/bjc.1980.29.
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The lethal activity and repair inhibition capacity of 1-(2-chloroethyl)-3-(2,6-dioxo-3-piperidyl)-1-nitrosourea (NSC 95466, PCNU), a nitrosourea with low carbamoylating activity.1-(2-氯乙基)-3-(2,6-二氧代-3-哌啶基)-1-亚硝基脲(NSC 95466,PCNU)的致死活性和修复抑制能力,一种具有低氨甲酰化活性的亚硝基脲
Invest New Drugs. 1983;1(3):197-202. doi: 10.1007/BF00208890.
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Clinical pharmacokinetics of commonly used anticancer drugs.常用抗癌药物的临床药代动力学
Clin Pharmacokinet. 1983 May-Jun;8(3):202-32. doi: 10.2165/00003088-198308030-00002.
6
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Cancer Chemother Pharmacol. 1985;14(2):125-31. doi: 10.1007/BF00434350.
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Antineoplastic drugs in 1990. A review (Part II).1990年的抗肿瘤药物。综述(第二部分)。
Drugs. 1990 May;39(5):652-73. doi: 10.2165/00003495-199039050-00003.