溶菌酶在梅毒螺旋体（Nichols株）免疫固定中的作用研究。
Studies on the action of lysozyme in immune immobilizaion of Treponema pallidium (Nichols strain).
作者信息
Müller F, Feddersen H, Segerling M
出版信息
Immunology. 1973 Apr;24(4):711-9.
Abstract
The action of antibodies and of the haemolytic complement system does not induce immune immobilization of , but only destroys superficial wall structures of these Gram-negative organisms. In sensitized and complement coated treponemes the immobilization is a result of the lysozyme interaction with the mucopeptide layer of the cell wall. In a lysozyme-free medium, immunologically damaged treponemes are able to repair the defects in the outer layers of their cell wall structures. Furthermore, it is shown that the long lag period in immune immobilization of can only partly be explained by the interaction of lysozyme with the treponemes.
摘要
抗体及溶血补体系统的作用并不会诱导这些革兰氏阴性菌的免疫固定，而仅仅破坏这些细菌的表面壁结构。在致敏且有补体包被的密螺旋体中，固定是溶菌酶与细胞壁粘肽层相互作用的结果。在无溶菌酶的培养基中，免疫受损的密螺旋体能够修复其细胞壁结构外层的缺陷。此外，研究表明，密螺旋体免疫固定中较长的延迟期仅部分可由溶菌酶与密螺旋体的相互作用来解释。
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The importance of different components of normal human serum and lysozyme in the rapid immobilisation of purified Treponema pallidum, Nichols strain.正常人血清和溶菌酶的不同成分在快速固定纯化的梅毒螺旋体Nichols株中的重要性。
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