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乙醇摄入期间的胃黏膜形态与粪便失血情况

Gastric mucosal morphology and faecal blood loss during ethanol ingestion.

作者信息

Dinoso V P, Meshkinpour H, Lorber S H

出版信息

Gut. 1973 Apr;14(4):289-92. doi: 10.1136/gut.14.4.289.

Abstract

The faecal blood loss of six alcoholic subjects with normal gastric mucosa, six with superficial gastritis, and six with atrophic gastritis was studied before and during ingestion of 40% v/v ethanol using (51)Cr-tagged red blood cells. No significant change in faecal blood loss was observed in the normal mucosa and superficial gastritis groups but all subjects with atrophic gastritis had significant increases of faecal blood loss during ethanol ingestion. These observations suggest that gastric mucosal morphology may be an important determinant of gastric mucosal bleeding during the ingestion of alcohol.

摘要

采用(51)铬标记红细胞的方法,对6名胃黏膜正常的酒精性受试者、6名患浅表性胃炎的受试者和6名患萎缩性胃炎的受试者在摄入体积分数为40%的乙醇之前和期间的粪便失血量进行了研究。正常黏膜组和浅表性胃炎组的粪便失血量未观察到显著变化,但所有萎缩性胃炎受试者在摄入乙醇期间粪便失血量均显著增加。这些观察结果表明,胃黏膜形态可能是饮酒期间胃黏膜出血的一个重要决定因素。

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本文引用的文献

2
Effects of alcohol on gastric mucosa.酒精对胃黏膜的影响。
Br Med J. 1956 Feb 4;1(4961):256-9. doi: 10.1136/bmj.1.4961.256.
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Gastritis: a revaluation.胃炎:重新评估
Medicine (Baltimore). 1954 Sep;33(3):199-290. doi: 10.1097/00005792-195409000-00002.
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Hemorrhagic gastritis. Importance of associated chronic gastritis.
Arch Intern Med. 1971 Jan;127(1):129-31. doi: 10.1001/archinte.127.1.129.
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Alcohol, aspirin, and gastrointestinal bleeding.酒精、阿司匹林与胃肠道出血。
Br Med J. 1968 Dec 14;4(5632):664-5. doi: 10.1136/bmj.4.5632.664.

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