阿司匹林与酒精和胃肠道出血
Aspirin and alcohol in gastrointestinal haemorrhage.
作者信息
Needham C D, Kyle J, Jones P F, Johnston S J, Kerridge D F
出版信息
Gut. 1971 Oct;12(10):819-21. doi: 10.1136/gut.12.10.819.
Abstract
The intake of aspirin, of alcohol, and of a combination of both, among 817 patients admitted for gastrointestinal haemorrhage is reported. The incidence of ingestion in six diagnostic groups is compared with that in two control groups. Analysis confirms that there is a markedly significant association between overt haemorrhage and the ingestion of aspirin, but this was not shown for alcohol taken alone: the combination of aspirin and alcohol showed a highly significant synergistic effect.
摘要
报告了817名因胃肠道出血入院患者的阿司匹林、酒精以及两者组合的摄入量情况。将六个诊断组的摄入发生率与两个对照组进行了比较。分析证实，显性出血与阿司匹林摄入之间存在显著的关联，但单独饮酒未显示出这种关联：阿司匹林与酒精的组合显示出高度显著的协同效应。
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