Ritchie J K, Lockhart-Mummery H E
Gut. 1973 Apr;14(4):263-9. doi: 10.1136/gut.14.4.263.
This study gives detailed information on the two principal groups of patients undergoing excisional surgery with a permanent artificial stoma for Crohn's disease of the large bowel. During the years 1952-71, 64 patients were treated by total proctocolectomy and ileostomy and 26 patients by excision of the distal large bowel and colostomy. In the group of patients undergoing proctocolectomy, there were two postoperative and six late deaths. Of the 56 patients alive at the end of the follow-up period (average length of follow-up 8.1 years), four had shown evidence of recurrent disease. In each case this occurred following a staged proctocolectomy and at, or immediately proximal to, the ileostomy: the shortest interval between surgery and recurrence was just under 10 years. AMONG THE PATIENTS TREATED BY EXCISION OF THE DISTAL LARGE BOWEL, THERE WERE TWO UNRELATED LATE DEATHS: with an average duration of follow up of 7.3 years, recurrent disease occurred in only one of the 24 patients alive at the concluding date for this study.
本研究提供了两组接受大肠克罗恩病永久性人工造口切除手术患者的详细信息。在1952年至1971年期间,64例患者接受了全直肠结肠切除术和回肠造口术,26例患者接受了远端大肠切除术和结肠造口术。在接受全直肠结肠切除术的患者组中,有2例术后死亡和6例晚期死亡。在随访期结束时存活的56例患者(平均随访时间8.1年)中,有4例出现了疾病复发迹象。在每种情况下,复发均发生在分期全直肠结肠切除术后,且在回肠造口处或其紧邻的近端:手术与复发之间的最短间隔略低于10年。在接受远端大肠切除术治疗的患者中,有2例与手术无关的晚期死亡:在本研究的截止日期时存活的24例患者中,只有1例在平均7.3年的随访期内出现了疾病复发。