[The influence of age and weight on the normal oral glucose tolerance (author's transl)].

The individual influence of age and weight on the normal glucose tolerance after an oral glucose load of 50 g was investigated in 332 test subjects (231 male + 101 female) presenting a healthy metabolism. The results show that, even within the range of normal glucose tolerance, the relative weight (age factor eliminated) exerts an influence both on the fasting blood sugar and on the 1 h-value (p less than or equal to 0.01), in women even on the 2 h-value (p less than or equal to 0.05) ("plain" glucose tolerance--weight correlation). The influence of the age factor (weight eliminated) on the normal glucose tolerance can only be demonstrated in the 1 h-value of men as sole value (p less than or equal to 0.01). Here it even slightly exceeds the influence of the weight factor ("plain" glucose tolerance--age correlation). Apart from this value, however, it can be stated that, within the normal glucose tolerance of both male and female subjects, the weight factor is of greater importance than the age factor. With increasing weight the sugar levels progressively approach the upper limit of the norm. Perhaps this is already the forefield to future secondary arteriopathies.