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48,XXXY的起源:Xg血型的证据。

Origin of 48,XXXY: the evidence of the Xg blood groups.

作者信息

Pfeiffer R A, Sanger R

出版信息

J Med Genet. 1973 Jun;10(2):142-3. doi: 10.1136/jmg.10.2.142.

Abstract

A third family is reported in which the Xg groups give information about the origin of an XXXY member: successive non-disjunction at the first and second paternal meiotic divisions is much the most likely cause. In the two previous informative families successive non-disjunction at maternal meiotic divisions was the most likely cause. An enquiry showed the average age of 29 fathers at the birth of XXXY sons to be 32-41 years.

摘要

据报道,有第三个家族,其中Xg血型群体为一名XXXY成员的起源提供了信息:最可能的原因是父本减数分裂第一次和第二次连续发生不分离。在前两个提供信息的家族中,最可能的原因是母本减数分裂连续发生不分离。一项调查显示,29位XXXY儿子出生时父亲的平均年龄为32至41岁。

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