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克罗恩病中脾脏制剂的白细胞迁移研究。

Leucocyte migration studies with spleen preparations in Crohn's disease.

作者信息

Richens E R, Gough K R, Williams M J

出版信息

Gut. 1973 May;14(5):376-9. doi: 10.1136/gut.14.5.376.

Abstract

Thirty-nine patients with Crohn's disease and 17 normal people were tested for hypersensitivity to sarcoid and normal spleen suspensions using the leucocyte migration test. In 26% of the Crohn's cases migration was inhibited, whereas inhibition was not significant in the control group. Migration inhibition did not appear to be related to duration or activity of the disease. Sixty-two percent of the Crohn's patients showed migration stimulation against normal spleen, a phenomenon that did not occur in the control group.

摘要

对39例克罗恩病患者和17名正常人进行了测试,采用白细胞迁移试验检测他们对结节病和正常脾脏悬液的超敏反应。在26%的克罗恩病病例中,迁移受到抑制,而在对照组中这种抑制并不显著。迁移抑制似乎与疾病的持续时间或活动度无关。62%的克罗恩病患者对正常脾脏表现出迁移刺激,这一现象在对照组中未出现。

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