结节病脾脏悬液对克罗恩病白细胞迁移的体外抑制作用
In-vitro inhibition of leucocyte migration in Crohn's disease by a sarcoid spleen suspension.
作者信息
Willoughby J M, Mitchell D N
出版信息
Br Med J. 1971 Jul 17;3(5767):155-7. doi: 10.1136/bmj.3.5767.155.
Abstract
A Kveim suspension has been shown to inhibit the migration of leucocytes in vitro from 12 out of 18 patients with Crohn's disease but to have no comparable effect on leucocytes from patients with ulcerative colitis or from a group of patients with other diseases. These findings provide further evidence of cross-reactivity or of a possible aetiological link between Crohn's disease and sarcoidosis and suggest a further immunological distinction between Crohn's disease and ulcerative colitis.
摘要
已证实，克维姆悬液在体外可抑制18例克罗恩病患者中12例的白细胞迁移，但对溃疡性结肠炎患者或其他疾病患者组的白细胞没有类似作用。这些发现进一步证明了克罗恩病与结节病之间存在交叉反应或可能的病因联系，并提示了克罗恩病与溃疡性结肠炎之间在免疫学上的进一步差异。
相似文献
1
In-vitro inhibition of leucocyte migration in Crohn's disease by a sarcoid spleen suspension.
Br Med J. 1971 Jul 17;3(5767):155-7. doi: 10.1136/bmj.3.5767.155.
2
Effect of sarcoid spleen suspension on in vitro leukocyte migration in Crohn's disease.
Gut. 1971 Jun;12(6):496.
3
Cellular hypersensitivity to components of intestinal mucosa in ulcerative colitis and Crohn's disease.
Gut. 1969 Aug;10(8):631-6. doi: 10.1136/gut.10.8.631.
4
A study of peripheral leucocyte migration in agarose medium in inflammatory bowel disease.
Gut. 1974 Apr;15(4):294-300. doi: 10.1136/gut.15.4.294.
5
Leucocyte migration inhibition with Kveim antigen in Crohn's disease.
Clin Exp Immunol. 1971 Dec;9(6):707-11.
6
Leukocyte migration test in Crohn's disease, ulcerative colitis, and ankylosing spondylitis using Crohn's colon homogenate, mitochondrial, and microsomal fractions.
Am J Dig Dis. 1975 May;20(5):425-9. doi: 10.1007/BF01070786.
7
Specific inhibition of the in vitro migration of leucocytes in ulcerative colitis and Crohn's disease.
Scand J Gastroenterol. 1967;2(3):214-21. doi: 10.3109/00365526709180072.
8
[The leucocyte-migration-inhibition-test in the diagnostic of sarcoidosis (author's transl)].
Arch Dermatol Res (1975). 1976 Nov 26;257(1):79-87. doi: 10.1007/BF00569116.
9
Human leucocyte antigens in Crohn's disease and ulcerative colitis.
Gut. 1972 Jun;13(6):438-40. doi: 10.1136/gut.13.6.438.
10
Cellular hypersensitivity in ulcerative colitis and Crohn's disease.
Schweiz Med Wochenschr. 1971 May 22;101(20):698-701.
引用本文的文献
1
The problem of chronic inflammatory bowel disease.
Calif Med. 1972 Jul;117(1):25-41.
2
A study of peripheral leucocyte migration in agarose medium in inflammatory bowel disease.
Gut. 1974 Apr;15(4):294-300. doi: 10.1136/gut.15.4.294.
3
Leucocyte migration studies in Crohn's disease using Crohn's colon homogenate and mitochondrial and microsomal fractions.
Gut. 1974 Jan;15(1):19-23. doi: 10.1136/gut.15.1.19.
4
Editorial: Forms of colitis.
Br Med J. 1973 Nov 17;4(5889):370-1.
5
The effect of gastric antigens on the in vitro migration of leucocytes from patients with atrophic gastritis and pernicious anaemia.
Clin Exp Immunol. 1973 Aug;14(4):501-8.
6
Leucocyte migration studies with spleen preparations in Crohn's disease.
Gut. 1973 May;14(5):376-9. doi: 10.1136/gut.14.5.376.
7
The Kmif (Kveim-induced macrophage migration inhibition factor) test in sarcoidosis.
J Clin Pathol. 1972 Nov;25(11):951-4. doi: 10.1136/jcp.25.11.951.
8
Impaired lymphocyte reactivity against tumour cells in patients with Crohn's disease.
Gut. 1972 Aug;13(8):614-20. doi: 10.1136/gut.13.8.614.
9
The effect of thyroid antigens on the in vitro migration of leucocytes from patients with Hashimoto thyroiditis.
Clin Exp Immunol. 1972 Dec;12(4):429-38.
10
Mixed-lymphocyte reaction as a measure of immunological competence of lymphocytes from patients with Crohn's disease.
Gut. 1974 Jan;15(1):24-8. doi: 10.1136/gut.15.1.24.
本文引用的文献
1
CROHN'S DISEASE OF THE LARGE INTESTINE.
Gut. 1964 Dec;5(6):493-509. doi: 10.1136/gut.5.6.493.
2
Specific inhibition of the in vitro migration of leucocytes in ulcerative colitis and Crohn's disease.
Scand J Gastroenterol. 1967;2(3):214-21. doi: 10.3109/00365526709180072.
3
Human lymphocyte migration as a parameter of hypersensitivity.
Acta Med Scand. 1967 Feb;181(2):247-56. doi: 10.1111/j.0954-6820.1967.tb07255.x.
4
Sarcoidosis. An in vitro Kveim reaction based on the leucocyte migration test.
Acta Pathol Microbiol Scand. 1969;76(3):493-4. doi: 10.1111/j.1699-0463.1969.tb03279.x.
5
6
An epidemiological study of ulcerative colitis and regional enteritis among adults in Baltimore. II. Social and demographic factors.
Gastroenterology. 1969 May;56(5):847-57.
7
Delayed hypersensitivity in Crohn's disease.
Proc R Soc Med. 1970 Sep;63(9):906-8. doi: 10.1177/003591577006300920.
8
Ulcerative and "granulomatous" colitis--validity of differential diagnostic criteria. A study of 100 patients treated by total colectomy.
Ann Intern Med. 1970 Jun;72(6):841-51. doi: 10.7326/0003-4819-72-6-841.
9
Comparative features and course of ulcerative and granulomatous colitis.
N Engl J Med. 1970 Mar 12;282(11):582-7. doi: 10.1056/NEJM197003122821102.
10
Lepromin and Kveim antigen reactivity in man, and their relation to tuberculin reactivity.
Br Med Bull. 1967 Jan;23(1):80-5. doi: 10.1093/oxfordjournals.bmb.a070522.
Zotero 插件