克罗恩病中玫瑰花结抑制试验的评估
An evaluation of the rosette inhibition test in Crohn's disease.
作者信息
Clarke J R, Richens E R, Williams M J, Gough K R, Ancill R J
出版信息
Gut. 1974 Sep;15(9):725-7. doi: 10.1136/gut.15.9.725.
Abstract
Serial rosette inhibition tests were performed on nine patients with Crohn's disease undergoing immunosuppressive therapy in an attempt to estimate the minimum amount of drug necessary to maintain immunosuppression. The rosette inhibition titre was found to be higher in immunosuppressed patients than in normal subjects. However, there was no consistent correlation of the rosette inhibition titre with the degree of activity of the disease. The test is therefore not sufficiently discriminative to be used as a basis on which to control drug dosage.
摘要
对9名正在接受免疫抑制治疗的克罗恩病患者进行了系列玫瑰花结抑制试验，以试图估算维持免疫抑制所需的最低药物剂量。结果发现，免疫抑制患者的玫瑰花结抑制效价高于正常受试者。然而，玫瑰花结抑制效价与疾病活动程度之间并无一致的相关性。因此，该试验的鉴别力不足，不能作为控制药物剂量的依据。
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