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潘科斯特瘤:高剂量放射治疗的价值

Pancoast tumor: the value of high dose radiation therapy.

作者信息

Morris R W, Abadir R

出版信息

Radiology. 1979 Sep;132(3):717-19. doi: 10.1148/132.3.717.

DOI:10.1148/132.3.717
PMID:472253
Abstract

Twenty-six patients with superior pulmonary sulcus (Pancoast) tumors were evaluated. Twelve patients were treated with high dose radiotherapy with NSD over 1 900 rets and 10 with NSD less than 1 900 rets. Four patients were treated with combined radiation and surgery. High dose radiotherapy resulted in relief of pain in all patients but apparently did not change survival. Low dose radiotherapy offered relief of pain to only half the patients. Distant metastasis was noted in 30% of patients (15% to brain, 3.8% to liver), rib destruction in 65% and supraclavicular nodes in 19%. Only 4 patients went to surgery and 2 died during operation. We thus conclude that Pancoast tumor is essentially an inoperable disease.

摘要

对26例肺上沟(潘科斯特)瘤患者进行了评估。12例患者接受了超过1900拉德的高剂量放疗(以皮肤剂量计),10例患者接受了低于1900拉德的放疗。4例患者接受了放疗与手术联合治疗。高剂量放疗使所有患者的疼痛得到缓解,但显然并未改变生存率。低剂量放疗仅使半数患者的疼痛得到缓解。30%的患者出现远处转移(15%转移至脑,3.8%转移至肝),65%的患者出现肋骨破坏,19%的患者出现锁骨上淋巴结转移。仅4例患者接受了手术,其中2例在手术中死亡。因此,我们得出结论,潘科斯特瘤本质上是一种无法手术的疾病。

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