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豚鼠气管中肾上腺素能神经的组织化学定位

Histochemical localization of adrenergic nerves in the guinea-pig trachea.

作者信息

O'Donnell S R, Saar N

出版信息

Br J Pharmacol. 1973 Apr;47(4):707-10. doi: 10.1111/j.1476-5381.1973.tb08197.x.

DOI:10.1111/j.1476-5381.1973.tb08197.x
PMID:4723795
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1776085/
Abstract
  1. Specific catecholamine fluorescence was demonstrated in guinea-pig trachea in fine, varicose, nerve fibres running parallel to the tracheal smooth muscle fibres.2. The density of nerves in tracheal smooth muscle was greater at the laryngeal end than at the bronchial end of the trachea.3. The findings confirm pharmacological evidence for an adrenergic innervation of the guinea-pig isolated tracheal chain preparation.
摘要

  1. 在豚鼠气管中，与气管平滑肌纤维平行走行的纤细、有曲张的神经纤维中显示出特异性儿茶酚胺荧光。

  2. 气管平滑肌中的神经密度在气管的喉端比支气管端更高。

  3. 这些发现证实了豚鼠离体气管链制剂肾上腺素能神经支配的药理学证据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a5a/1776085/9c2308916e6d/brjpharm00550-0033-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a5a/1776085/1b40e73d2706/brjpharm00550-0033-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a5a/1776085/9c2308916e6d/brjpharm00550-0033-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a5a/1776085/1b40e73d2706/brjpharm00550-0033-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a5a/1776085/9c2308916e6d/brjpharm00550-0033-b.jpg

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1
Histochemical localization of adrenergic nerves in the guinea-pig trachea.豚鼠气管中肾上腺素能神经的组织化学定位
Br J Pharmacol. 1973 Apr;47(4):707-10. doi: 10.1111/j.1476-5381.1973.tb08197.x.
2
Tne density of adrenergic nerves at various levels in the guinea-pig lung.
Clin Exp Pharmacol Physiol. 1978 Jul-Aug;5(4):325-32. doi: 10.1111/j.1440-1681.1978.tb00681.x.
3
Extrinsic pathways of the adrenergic innervation of the guinea-pig trachealis muscle.豚鼠气管平滑肌肾上腺素能神经支配的外在途径。
J Auton Nerv Syst. 1985 Sep;14(1):61-73. doi: 10.1016/0165-1838(85)90125-0.
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Innervation of the guinea pig trachea: a quantitative morphological study of intrinsic neurons and extrinsic nerves.豚鼠气管的神经支配：对内在神经元和外在神经的定量形态学研究
J Comp Neurol. 1989 Jul 1;285(1):117-32. doi: 10.1002/cne.902850110.
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Evidence for nonadrenergic inhibitory nerves in the guinea pig trachealis muscle.豚鼠气管平滑肌中非肾上腺素能抑制性神经的证据。
Am J Physiol. 1973 May;224(5):1072-80. doi: 10.1152/ajplegacy.1973.224.5.1072.
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A histochemical study of extraneuronal accumulation of noradrenaline in the guinea-pig trachea.豚鼠气管中去甲肾上腺素细胞外积聚的组织化学研究。
Br J Pharmacol. 1973 Oct;49(2):267-78. doi: 10.1111/j.1476-5381.1973.tb08372.x.
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Evidence that adrenergic nerves are responsible for the active uptake of noradrenaline in the guinea-pig isolated trachea.有证据表明，在豚鼠离体气管中，肾上腺素能神经负责去甲肾上腺素的主动摄取。
Br J Pharmacol. 1975 Jan;53(1):109-12. doi: 10.1111/j.1476-5381.1975.tb07336.x.
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Evidence for inhibition of sympathetic neurotransmission by endogenously released acetylcholine in the guinea-pig trachea.豚鼠气管中内源性释放的乙酰胆碱对交感神经传递的抑制作用的证据。
Br J Pharmacol. 1991 Dec;104(4):817-22. doi: 10.1111/j.1476-5381.1991.tb12512.x.
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[Nonadrenergic noncholinergic inhibitory nervous system in guinea pig airway].[豚鼠气道中的非肾上腺素能非胆碱能抑制性神经系统]
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引用本文的文献

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Reflex regulation of airway sympathetic nerves in guinea-pigs.豚鼠气道交感神经的反射调节
J Physiol. 2006 Jun 1;573(Pt 2):549-64. doi: 10.1113/jphysiol.2005.104661. Epub 2006 Mar 31.
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Relaxant innervation of the guinea-pig trachealis: demonstration of capsaicin-sensitive and -insensitive vagal pathways.豚鼠气管的舒张性神经支配：辣椒素敏感和不敏感迷走神经通路的证明。
J Physiol. 1993 Jan;460:719-39. doi: 10.1113/jphysiol.1993.sp019496.
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Innervation of the trachealis muscle in the guinea-pig: a quantitative ultrastructural study.

本文引用的文献

1
A NOTE ON THE ELECTRICALLY TRANSMURALLY STIMULATED ISOLATED TRACHEA OF THE GUINEA-PIG.关于电经壁刺激豚鼠离体气管的一则笔记。
J Pharm Pharmacol. 1964 Feb;16:125-8. doi: 10.1111/j.2042-7158.1964.tb07431.x.
2
The potentiation of the responses to noradrenaline and isoprenaline of the guinea-pig isolated tracheal chain preparation by desipramine, cocaine, phentolamine, phenoxybenzamine, guanethidine, metanephrine and cooling.去甲丙咪嗪、可卡因、酚妥拉明、酚苄明、胍乙啶、变肾上腺素及冷却对豚鼠离体气管链制备物对去甲肾上腺素和异丙肾上腺素反应的增强作用。
Br J Pharmacol Chemother. 1967 Nov;31(3):466-82. doi: 10.1111/j.1476-5381.1967.tb00412.x.
3
豚鼠气管肌的神经支配：一项定量超微结构研究。
J Anat. 1980 Jun;130(Pt 4):789-800.
4
Direct and indirect actions of dopamine on tracheal smooth muscle.多巴胺对气管平滑肌的直接和间接作用。
Naunyn Schmiedebergs Arch Pharmacol. 1980;315(1):15-20. doi: 10.1007/BF00504225.
5
Noradrenergic inhibitory innervation of the lung.肺的去甲肾上腺素能抑制性神经支配。
Lung. 1981;159(6):315-22. doi: 10.1007/BF02713931.
6
A histochemical study of extraneuronal accumulation of noradrenaline in the guinea-pig trachea.豚鼠气管中去甲肾上腺素细胞外积聚的组织化学研究。
Br J Pharmacol. 1973 Oct;49(2):267-78. doi: 10.1111/j.1476-5381.1973.tb08372.x.
7
Determination of extrinsic pathways of adrenergic nerves to the guinea-pig trachealis muscle using surgical denervation and organ-bath pharmacology.利用手术去神经支配和器官浴药理学方法测定豚鼠气管平滑肌肾上腺素能神经的外在途径。
Agents Actions. 1986 Oct;19(1-2):48-54. doi: 10.1007/BF01977255.
8
Inhibitory responses to nicotine and transmural stimulation in hyoscine-treated guinea-pig isolated trachealis: an electrical and mechanical study.东莨菪碱处理的豚鼠离体气管对尼古丁和跨壁刺激的抑制反应：电生理和力学研究
Br J Pharmacol. 1987 Apr;90(4):733-44. doi: 10.1111/j.1476-5381.1987.tb11227.x.
9
A physiological basis for subclassifying beta-adrenoceptors examined by chemical sympathectomy of guinea-pigs.通过豚鼠化学性交感神经切除术研究β-肾上腺素能受体亚分类的生理基础。
J Physiol. 1986 Apr;373:367-78. doi: 10.1113/jphysiol.1986.sp016053.
10
Neuronally released (-)-noradrenaline relaxes smooth muscle of calf trachea mainly through beta 1-adrenoceptors: comparison with (-)-adrenaline and relation to adenylate cyclase stimulation.神经元释放的（-）-去甲肾上腺素主要通过β1-肾上腺素能受体使小牛气管平滑肌松弛：与（-）-肾上腺素的比较及与腺苷酸环化酶刺激的关系。
Naunyn Schmiedebergs Arch Pharmacol. 1989 Jan-Feb;339(1-2):85-98. doi: 10.1007/BF00165131.
Localization of catechol amines in visceral organs and ganglia of the rat, guinea-pig and rabbit.
大鼠、豚鼠和家兔内脏器官及神经节中儿茶酚胺的定位
Br J Pharmacol Chemother. 1965 Oct;25(2):307-16. doi: 10.1111/j.1476-5381.1965.tb02051.x.
4
The interaction of cocaine and propranolol with catecholamines on guinea pig trachea.可卡因与普萘洛尔在豚鼠气管上与儿茶酚胺的相互作用。
Eur J Pharmacol. 1967 Nov;2(2):77-82. doi: 10.1016/0014-2999(67)90028-3.
5
Some evidence of the active uptake of noradrenaline in the guinea-pig isolated trachea.在豚鼠离体气管中去甲肾上腺素主动摄取的一些证据。
Br J Pharmacol. 1972 May;45(1):71-82. doi: 10.1111/j.1476-5381.1972.tb09578.x.
6
The effect on some receptors of guinea pig trachea of a series of sympathomimetics amines.
Eur J Pharmacol. 1971 Oct;16(2):201-8. doi: 10.1016/0014-2999(71)90011-2.