Weinbren K, Washington S, Dowling F
Br J Exp Pathol. 1973 Aug;54(4):429-36.
An attempt has been made to isolate the component mechanisms involved in the proliferative response of the rat liver after partial hepatectomy. The exclusion of portal haemodynamic factors was effected by portacaval anastomosis and the influence of major endocrine gland activity by hypophysectomy. Rats in which both these surgical procedures had been performed showed evidence of a hepatic restorative response after partial hepatectomy.
人们试图分离部分肝切除术后大鼠肝脏增殖反应所涉及的组成机制。通过门腔静脉吻合术排除门静脉血流动力学因素,并通过垂体切除排除主要内分泌腺活动的影响。接受了这两种外科手术的大鼠在部分肝切除术后表现出肝脏恢复反应的迹象。