用二氮嗪治疗的高血压患者锥体外系症状的发展。
Development of extrapyramidal symptoms in hypertensive patients treated with diazoxide.
作者信息
Neary D, Thurston H, Pohl J E
出版信息
Br Med J. 1973 Sep 1;3(5878):474-5. doi: 10.1136/bmj.3.5878.474.
Abstract
Extrapyramidal symptoms developed a variable time after the start of treatment with oral diazoxide in 15% of a series of 100 severely hypertensive patients. Six illustrative cases are described. Treatment with diazoxide could be continued in four of these. The symptoms are usually controllable either by dosage adjustment or by the use of diazepam or procyclidine. There was no evidence of irreversibility of the extrapyramidal syndromes observed.
摘要
在100例严重高血压患者中，15%在开始口服二氮嗪治疗后的不同时间出现锥体外系症状。描述了6个典型病例。其中4例患者可继续使用二氮嗪治疗。这些症状通常可通过调整剂量或使用地西泮或丙环定来控制。未观察到锥体外系综合征有不可逆的证据。
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