• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

吲哚洛芬(K 4277)镇痛作用的双盲研究。

Double-blind study of the analgesic effect of indoprofen (K 4277).

作者信息

Fuccella L M, Conti F, Corvi G, Mandelli V, Randelli M, Stefanelli G

出版信息

Clin Pharmacol Ther. 1975 Mar;17(3):277-83. doi: 10.1002/cpt1975173277.

DOI:10.1002/cpt1975173277
PMID:47280
Abstract

In a double-blind study, indoprofen was superior to placebo in decreasing pain in patients with primary and metastatic cancer and with neuralgia. A single oral dose of 200 mg was more active than a 100-mg dose. The preferences of patients proved to be a more sensitive parameter in this study than scores of pain intensity, pain relief, and other related measurements (SPID, TOTPAR, and Peak PID).

摘要

在一项双盲研究中,吲哚美辛在减轻原发性和转移性癌症患者以及神经痛患者的疼痛方面优于安慰剂。单次口服200毫克的剂量比100毫克的剂量活性更强。在本研究中,患者的偏好被证明是一个比疼痛强度评分、疼痛缓解及其他相关测量指标(SPID、TOTPAR和Peak PID)更敏感的参数。

相似文献

1
Double-blind study of the analgesic effect of indoprofen (K 4277).吲哚洛芬(K 4277)镇痛作用的双盲研究。
Clin Pharmacol Ther. 1975 Mar;17(3):277-83. doi: 10.1002/cpt1975173277.
2
Indoprofen, a new analgesic and anti-inflammatory drug in cancer pain.
Clin Pharmacol Ther. 1975 Mar;17(3):284-9. doi: 10.1002/cpt1975173284.
3
Application of nonparametric procedure for bioassay data to the evaluation of analgesics in man.生物测定数据的非参数方法在人体镇痛药评估中的应用。
J Clin Pharmacol. 1977 Apr;17(4):177-84. doi: 10.1177/009127007701700401.
4
A comparative oral analgesic study of indoprofen, aspirin, and placebo in postpartum pain.
J Clin Pharmacol. 1985 Jul-Aug;25(5):374-80. doi: 10.1002/j.1552-4604.1985.tb02858.x.
5
Double-blind cross-over study of ketoprofen and ibuprofen in management of rheumatoid arthritis.酮洛芬与布洛芬治疗类风湿性关节炎的双盲交叉研究
Br Med J. 1973 Oct 13;4(5884):82-4. doi: 10.1136/bmj.4.5884.82.
6
An analgesic comparison study of indoprofen versus aspirin and placebo in surgical pain.吲哚美辛与阿司匹林及安慰剂治疗手术疼痛的镇痛效果比较研究
J Clin Pharmacol. 1979 Aug-Sep;19(8-9 Pt 1):487-92. doi: 10.1002/j.1552-4604.1979.tb02511.x.
7
Indoprofen and pentazocine in post-traumatic pain. A double-blind, parallel-group comparative trial.
J Int Med Res. 1983;11(6):354-8. doi: 10.1177/030006058301100606.
8
[Preliminary study on hemodynamics in heart patients treated with a single dose of indoprofen].[单剂量吲哚美辛治疗心脏病患者的血流动力学初步研究]
Clin Ter. 1976 Nov 30;79(4):339-46.
9
Biliary colic as a model for assessing analgesic activity in man.以胆绞痛作为评估人体镇痛活性的模型。
J Pharmacol Exp Ther. 1977 May;201(2):444-9.
10
Clinically controlled comparative study of intravenous single doses of suprofen versus indoprofen.静脉注射单剂量舒洛芬与吲哚洛芬的临床对照比较研究。
Arzneimittelforschung. 1986 Jul;36(7):1104-7.

引用本文的文献

1
Nonsteroidal anti-inflammatory drugs and pain in cancer patients: a systematic review and reappraisal of the evidence.非甾体抗炎药与癌症患者的疼痛:系统评价与证据再评估。
Br J Anaesth. 2019 Aug;123(2):e412-e423. doi: 10.1016/j.bja.2019.02.028. Epub 2019 May 20.
2
Response of pathological ischaemic muscle pain to analgesics.病理性缺血性肌肉疼痛对镇痛药的反应。
Br J Clin Pharmacol. 1980 Feb;9(2):165-9. doi: 10.1111/j.1365-2125.1980.tb05828.x.
3
Lumbar epidural morphine as an effective analgesic following cholecystectomy.
Can Anaesth Soc J. 1981 Nov;28(6):523-9. doi: 10.1007/BF03007147.
4
Effect of analgesic agents on emptying of the gallbladder in man.镇痛药对人体胆囊排空的影响。
Eur J Clin Pharmacol. 1976 Jun 15;10(2):127-31. doi: 10.1007/BF00609471.