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An aberrant nucleus in the telencephalon following administration of ENU during neuroembryogenesis.

作者信息

Hallas B H, Das G D

出版信息

Teratology. 1979 Apr;19(2):159-64. doi: 10.1002/tera.1420190205.

DOI:10.1002/tera.1420190205
PMID:473069
Abstract

Administration of ENU to rats during embryonic development caused the emergence of aberrant nuclei in the dorsal telencephalon. They were located in the corpus callosum, and were composed of pyramidal and stellate neurons. This suggested that the aberrant nuclei arose out of the neurons of cerebral cortex that had failed to migrate during embryogenesis. The aberrant nuclei were found predominantly in the animals receiving ENU on day 18 or earlier of gestation.

摘要

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