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Role of cytochrome P-450 in carbon tetrachloride activation and CCl 4-induced necrosis. Effect of inhibitors of heme synthesis. I. 3-Amino-1,2,4 triazole.

作者信息

D'Acosta N, Castro J A, Díaz Gòmez M I, de Ferreyra E C, de Castro C R, de Fenos O M

出版信息

Res Commun Chem Pathol Pharmacol. 1973 Jul;6(1):175-83.

PMID:4733995
Abstract
摘要

相似文献

1
Role of cytochrome P-450 in carbon tetrachloride activation and CCl 4-induced necrosis. Effect of inhibitors of heme synthesis. I. 3-Amino-1,2,4 triazole.细胞色素P - 450在四氯化碳活化及四氯化碳诱导坏死中的作用。血红素合成抑制剂的影响。I. 3 - 氨基 - 1,2,4 - 三唑
Res Commun Chem Pathol Pharmacol. 1973 Jul;6(1):175-83.
2
2-Propanol treatment induces selectively the metabolism of carbon tetrachloride to phosgene. Implications for carbon tetrachloride hepatotoxicity.2-丙醇处理选择性地诱导四氯化碳代谢为光气。对四氯化碳肝毒性的影响。
Drug Metab Dispos. 1981 Nov-Dec;9(6):551-6.
3
Effect of 3-amino-1,2,4-triazole on the stimulation of hepatic microsomal heme synthesis and induction of hepatic microsomal oxidases produced by phenobarbital.3-氨基-1,2,4-三唑对苯巴比妥刺激肝微粒体血红素合成及诱导肝微粒体氧化酶的影响。
Mol Pharmacol. 1969 Jan;5(1):10-20.
4
Selective protection of curcumin against carbon tetrachloride-induced inactivation of hepatic cytochrome P450 isozymes in rats.姜黄素对四氯化碳诱导的大鼠肝细胞色素P450同工酶失活的选择性保护作用。
Life Sci. 2006 Apr 4;78(19):2188-93. doi: 10.1016/j.lfs.2005.09.025. Epub 2005 Nov 8.
5
A comparison of the effects of halothane and CCl 4 on the hepatic drug metabolizing system.氟烷和四氯化碳对肝脏药物代谢系统影响的比较。
J Pharmacol Exp Ther. 1971 Jun;177(3):556-66.
6
A proposed mechanism for the destruction of cytochrome P450 during carbon tetrachloride metabolism.一种在四氯化碳代谢过程中细胞色素P450被破坏的推测机制。
Proc West Pharmacol Soc. 1977;20:97-102.
7
Dibenamine impairment of rat hepatic microsomal enzymes and its relation to hepatotoxicity induced by CCl4 and dimethylnitrosamine.二苯那明对大鼠肝微粒体酶的损害及其与四氯化碳和二甲基亚硝胺所致肝毒性的关系。
Drug Metab Dispos. 1974 Sep-Oct;2(5):464-8.
8
[Heterogeneity in the distribution of cytochrome P-450 in the liver lobule revealed on exposure to carbon tetrachloride].[四氯化碳暴露后肝小叶中细胞色素P - 450分布的异质性]
Biull Eksp Biol Med. 1979 Apr;87(4):364-6.
9
The stimulation of lipid peroxidation produced by dimethylnitrosamine in rat liver microsomes in vitro: the effects of promethazine and inhibitors of drug metabolism, and a comparison with previous studies using carbon tetrachloride.二甲基亚硝胺在体外对大鼠肝微粒体脂质过氧化的刺激作用：异丙嗪及药物代谢抑制剂的影响，以及与既往使用四氯化碳的研究比较
Xenobiotica. 1973 Jun;3(6):357-66. doi: 10.3109/00498257309151528.
10
Immunohistochemical evidence for alterations in specific forms of rat hepatic microsomal cytochrome P-450 during acute carbon tetrachloride intoxication.
Drug Metab Dispos. 1986 Nov-Dec;14(6):709-13.

引用本文的文献

1
Pyrazole prevention of CC14-induced ultrastructural changes in rat liver.吡唑对四氯化碳诱导的大鼠肝脏超微结构变化的预防作用。
Br J Exp Pathol. 1980 Oct;61(5):505-11.
2
Carbon tetrachloride activation by highly purified liver mitochondrial preparations.
Agents Actions. 1984 Dec;15(5-6):664-7. doi: 10.1007/BF01966789.
3
Carbon tetrachloride-induced early biochemical alterations but not necrosis in pigeon's liver.
Agents Actions. 1984 Oct;15(3-4):463-6. doi: 10.1007/BF01972389.