组蛋白对豚鼠接种A-爱知-2-68（H3N2）流感病毒后抗体反应的影响。
Influence of histones on the antibody response in guinea pigs to vaccination with A-Aichi-2-68 (H3 N2) influenza virus.
作者信息
Drescher J, Gillissen G
出版信息
Infect Immun. 1973 Oct;8(4):573-6. doi: 10.1128/iai.8.4.573-576.1973.
Abstract
The influence of total, F1, and F3 histones on the primary antibody response in guinea pigs to vaccination with influenza virus A/2/Aichi/2/68 (H3 N2) was investigated. It was found that histones can greatly reduce the immunoglobulin (Ig) M and, to a smaller degree, the IgG antibody response. The immunosuppressive effect of histones was found to depend critically on the dose of virus used for vaccination, on the type and dose of histones, and on the schedule of histone application.
摘要
研究了总组蛋白、F1组蛋白和F3组蛋白对豚鼠针对甲型流感病毒A/2/爱知/2/68（H3N2）疫苗接种的初次抗体反应的影响。结果发现，组蛋白可显著降低免疫球蛋白（Ig）M抗体反应，对IgG抗体反应的降低程度较小。还发现组蛋白的免疫抑制作用严重依赖于用于疫苗接种的病毒剂量、组蛋白的类型和剂量以及组蛋白的应用方案。
相似文献
1
Influence of histones on the antibody response in guinea pigs to vaccination with A-Aichi-2-68 (H3 N2) influenza virus.组蛋白对豚鼠接种A-爱知-2-68（H3N2）流感病毒后抗体反应的影响。
Infect Immun. 1973 Oct;8(4):573-6. doi: 10.1128/iai.8.4.573-576.1973.
2
3
Secretory and systemic cell-mediated and humoral immune response in humans and guinea pigs to the inactivated influenza virus vaccine.人类和豚鼠对灭活流感病毒疫苗的分泌性及全身性细胞介导免疫和体液免疫反应。
Adv Exp Med Biol. 1972;31(0):87-95. doi: 10.1007/978-1-4684-3225-1_8.
4
Mucosal vaccination against influenza: protection of pigs immunized with inactivated virus and ether-split vaccine.流感的黏膜疫苗接种：用灭活病毒和乙醚裂解疫苗免疫猪的保护作用。
Jpn J Vet Res. 2001 Feb;48(4):197-203.
5
Antibody and immunoglobulin response to antirabies vaccination in man.人体抗狂犬病疫苗接种后的抗体及免疫球蛋白反应。
Infect Immun. 1972 Oct;6(4):483-6. doi: 10.1128/iai.6.4.483-486.1972.
6
Antibody response in humans to neuraminidase of A2-Aichi-68 and B-Mass-66 influenza viruses.人类对A2-爱知-68型和B-马赛-66型流感病毒神经氨酸酶的抗体反应。
Proc Soc Exp Biol Med. 1971 Oct;138(1):47-51.
7
Mercaptoethanol-sensitive antibody production in germ-free mice and guinea pigs.无菌小鼠和豚鼠中对巯基乙醇敏感的抗体产生
J Immunol. 1965 Aug;95(2):300-5.
8
9
The humoral immune response and protective efficacy of vaccination with inactivated split and whole influenza virus vaccines in BALB/c mice.灭活裂解流感病毒疫苗和全病毒疫苗对BALB/c小鼠的体液免疫应答及免疫保护效果
Vaccine. 2006 Nov 10;24(44-46):6585-7. doi: 10.1016/j.vaccine.2006.05.040. Epub 2006 Jun 5.
本文引用的文献
1
Further fractionations of histones from calf thymus.来自小牛胸腺组蛋白的进一步分级分离。
Biochem J. 1962 Jan;82(1):15-8. doi: 10.1042/bj0820015.
2
INTERRUPTION OF MACROGLOBULIN SYNTHESIS IN MICE BY EXPOSURE TO X-RAYS.通过暴露于X射线中断小鼠中的巨球蛋白合成。
J Immunol. 1964 Aug;93:315-8.
3
THE NATURE OF ANTIBODIES IN MICE INJECTED WITH INFLUENZA VIRUS VACCINE.注射流感病毒疫苗的小鼠体内抗体的性质
Proc Soc Exp Biol Med. 1963 Aug-Sep;113:1013-6. doi: 10.3181/00379727-113-28560.
4
Assay of nucleic acids by means of the photometric hemaggregation test.通过光度血凝试验检测核酸
Arch Biochem Biophys. 1967 Aug;121(2):346-51. doi: 10.1016/0003-9861(67)90086-0.
5
Rabbit antibodies induced by calf thymus histone-serum albumin complexes.由小牛胸腺组蛋白 - 血清白蛋白复合物诱导产生的兔抗体。
J Immunol. 1967 Jun;98(6):1182-9.
6
The antigenic subunits of influenza viruses. I. The homologous antibody response.流感病毒的抗原亚单位。I. 同源抗体反应。
J Immunol. 1969 Nov;103(5):1099-106.
7
[Effect exerted by a histone fraction (P II) on the formation of antibodies].[组蛋白组分（P II）对抗体形成的作用]
C R Acad Hebd Seances Acad Sci D. 1968 Apr 1;266(14):1540-2.
8
[Immunosuppressive effect of histone on the model of skin transplantation. Comparative studies with cyclophosphamide].[组蛋白对皮肤移植模型的免疫抑制作用。与环磷酰胺的比较研究]
Z Gesamte Exp Med Einschl Exp Chir. 1970 Aug 23;152(4):335-51.
9
[Immunosuppressive effect, in mice, of histones and theirJohn's Fl fraction].
Rev Fr Etud Clin Biol. 1969 Aug-Sep;14(7):663-70.
10
Rabbit precipitin antibody to chicken erythrocyte histone F2C.针对鸡红细胞组蛋白F2C的兔沉淀素抗体。
J Immunol. 1972 Oct;109(4):686-91.
Zotero 插件