利用富含¹³C的前体物质和碳磁共振研究利福霉素的生物合成。 - Suppr | 超能文献

Rifamycin biosynthesis studied with 13C enriched precursors and carbon magnetic resonance.

作者信息

White R J, Martinelli E, Gallo G G, Lancini G, Beynon P

出版信息

Nature. 1973 Jun 1;243(5405):273-7. doi: 10.1038/243273a0.

DOI:10.1038/243273a0

Abstract

摘要

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Nature. 1973 Jun 1;243(5405):273-7. doi: 10.1038/243273a0.

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B-factor, an essential regulatory substance inducing the production of rifamycin in a Nocardia sp.B因子，一种诱导诺卡氏菌属中利福霉素产生的必需调节物质。

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A genetic approach to the biosynthesis of the rifamycin-chromophore in Nocardia mediterranei. I. Isolation and characterization of a pentose-excreting auxotrophic mutant of Nocardia mediterranei with drastically reduced rifamycin production.地中海诺卡氏菌中利福霉素发色团生物合成的遗传学方法。I. 一株产利福霉素大幅减少的分泌戊糖的地中海诺卡氏菌营养缺陷型突变体的分离与鉴定。

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[Biosynthesis of the labelled rifamycin B in the presence of different 14C- and 3H-precursors].[在不同的¹⁴C和³H前体存在下标记利福霉素B的生物合成]

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A genetic approach to the biosynthesis of the rifamycin-chromophore in Nocardia mediterranei. IV. Identification of 3-amino-5-hydroxybenzoic acid as a direct precursor of the seven-carbon amino starter-unit.

J Antibiot (Tokyo). 1981 Jan;34(1):64-71. doi: 10.7164/antibiotics.34.64.

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A genetic approach to the biosynthesis of the rifamycin-chromophore in Nocardia mediterranei. II. Isolation and characterization of a shikimate excreting auxotrophic mutant of Nocardia mediterranei with normal rifamycin-production.地中海诺卡氏菌中利福霉素发色团生物合成的遗传学方法。II. 一株产利福霉素正常但分泌莽草酸的地中海诺卡氏菌营养缺陷型突变体的分离与鉴定。

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Ansamycin biogenesis: studies on a novel rifamycin isolated from a mutant strain of Nocardia mediterranei.安莎霉素生物合成：对从地中海诺卡氏菌突变株中分离出的一种新型利福霉素的研究。

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Genetics of antibiotic production.抗生素生产的遗传学

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