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孟加拉乡村儿童的乳糖吸收不良:与年龄、近期腹泻史、营养状况及母乳喂养的关系

Lactose malabsorption in Bangladeshi village children: relation with age, history of recent diarrhea, nutritional status, and breast feeding.

作者信息

Brown K H, Parry L, Khatun M, Ahmed G

出版信息

Am J Clin Nutr. 1979 Sep;32(9):1962-9. doi: 10.1093/ajcn/32.9.1962.

Abstract

The prevalence of lactose malabsorption (LM) among Bangladeshi village children has been determined using the recent developed breath hydrogen test. Initial hospital-based comparison studies showed general agreement between the breath hydrogen test and a modified lactose tolerance test. Two hundred thirty-four children, stratified by age, nutritional status, and history of recent diarrhea then participated in the field study. LM was diagnosed in more than 80% of children over 36 months of age but in none of the children under 6 months. Rates of LM were significantly increased in children with a history of recent diarrhea and a greater proportion of children in some age groups evidenced malabsorption in association with acute undernutrition. In the weanling age group children who were still breast feeding had a lower rate of LM than fully weaned subjects.

摘要

利用最近开发的呼气氢试验测定了孟加拉国农村儿童乳糖吸收不良(LM)的患病率。最初基于医院的比较研究表明,呼气氢试验与改良乳糖耐量试验结果基本一致。随后,234名按年龄、营养状况和近期腹泻史分层的儿童参与了实地研究。36个月以上儿童中超过80%被诊断为乳糖吸收不良,而6个月以下儿童无一被诊断为此病。近期有腹泻史的儿童乳糖吸收不良发生率显著增加,部分年龄组中更大比例的儿童存在与急性营养不良相关的吸收不良。在断奶年龄组中,仍在母乳喂养的儿童乳糖吸收不良发生率低于完全断奶的儿童。

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