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乳糖吸收不良与乳糖不耐受:对一般牛奶消费的影响

Lactose malabsorption and lactose intolerance: implications for general milk consumption.

作者信息

Torún B, Solomons N W, Viteri F E

出版信息

Arch Latinoam Nutr. 1979 Dec;29(4):445-94.

PMID:121688
Abstract

A total of 194 publications related to lactose malabsorption or intolerance were reviewed. The poor correlation between lactose malabsorption and intolerance to the amounts of milk ordinarily ingested in a meal, indicates that the assumption of milk tolerance by many populations is exaggerated. The methods for the diagnosis of these conditions were critically evaluated and it is suggested that, a) "physiological" doses of lactose be used; b) milk is the vehicle of choice; c) tests of intolerance be double-blind, and d) analysis of breath hydrogen be used for malabsorption. Most of the evidence indicates that milk consumption allows adequate growth of children, even when they are malnourished and have diarrhea. Nevertheless, it is recommended to substitute temporarily non-human milk by other good sources of dietary protein and energy during episodes of severe diarrhea, and to reintroduce milk to the diet gradually during convalescence. Breast feeding, however, should not be interrupted. These is not enough scientific nor epidemiological support to justify discouraging the use of milk in food supplementation programs, but several aspects that must be considered in such programs are outlined.

摘要

共查阅了194篇与乳糖吸收不良或不耐受相关的文献。乳糖吸收不良与一餐中通常摄入的牛奶量不耐受之间的相关性较差,这表明许多人群对牛奶耐受性的假设被夸大了。对这些病症的诊断方法进行了严格评估,并建议:a)使用“生理”剂量的乳糖;b)牛奶是首选载体;c)不耐受测试应采用双盲法;d)采用呼气氢分析来检测吸收不良。大多数证据表明,即使儿童营养不良且患有腹泻,饮用牛奶也能使其充分生长。然而,建议在严重腹泻期间暂时用其他优质的膳食蛋白质和能量来源替代母乳,并在康复期间逐渐将牛奶重新引入饮食中。不过,母乳喂养不应中断。目前尚无足够的科学或流行病学依据来支持在食物补充计划中不鼓励使用牛奶,但文中概述了此类计划中必须考虑的几个方面。

相似文献

1
Lactose malabsorption and lactose intolerance: implications for general milk consumption.乳糖吸收不良与乳糖不耐受:对一般牛奶消费的影响
Arch Latinoam Nutr. 1979 Dec;29(4):445-94.
2
Lactose malabsorption in Bangladeshi village children: relation with age, history of recent diarrhea, nutritional status, and breast feeding.孟加拉乡村儿童的乳糖吸收不良:与年龄、近期腹泻史、营养状况及母乳喂养的关系
Am J Clin Nutr. 1979 Sep;32(9):1962-9. doi: 10.1093/ajcn/32.9.1962.
3
[Milk intolerance in Colombian children, its prevalence and relation to lactose malabsorption].[哥伦比亚儿童的牛奶不耐受情况、患病率及其与乳糖吸收不良的关系]
Arch Latinoam Nutr. 1979 Sep;29(3):329-39.
4
The effect of dietary lactose on the early recovery from protein-energy malnutrition. II. Indices of nutrient absorption.膳食乳糖对蛋白质-能量营养不良早期恢复的影响。II. 营养吸收指标。
Am J Clin Nutr. 1984 Sep;40(3):601-10. doi: 10.1093/ajcn/40.3.601.
5
Carbohydrate malabsorption in children with severe protein energy malnutrition.重度蛋白质能量营养不良儿童的碳水化合物吸收不良
Trop Geogr Med. 1984 Dec;36(4):355-65.
6
Lactose intolerance in protein-energy malnutrition: a clinical case study and family study using a hydrogen (H2) breath-analysis test for carbohydrate malabsorption.蛋白质-能量营养不良中的乳糖不耐受:一项使用氢气(H2)呼气分析测试评估碳水化合物吸收不良的临床病例研究及家系研究
Arq Gastroenterol. 1979 Jul-Sep;16(3):137-45.
7
Lactose intolerance and diarrhea: are they related?乳糖不耐受与腹泻:它们有关联吗?
Pediatr Ann. 1985 Jan;14(1):62-3, 66-7, 70-1 passim. doi: 10.3928/0090-4481-19850101-10.
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Perspective on milk-drinking and malabsorption of lactose.关于饮用牛奶与乳糖吸收不良的观点。
Pediatrics. 1977 Jan;59(1):98-108.
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[Intolerance to powdered milk in Senegalese children presenting lactose malabsorption].[塞内加尔乳糖吸收不良儿童对奶粉的不耐受情况]
Can J Public Health. 1982 Sep-Oct;73(5):341-4.
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[Determination of milk and diary products consumption and their connection with lactose malabsorption or lactose intolerance in selected disorders of the alimentary tract in children].[儿童消化道某些疾病中牛奶及奶制品摄入量的测定及其与乳糖吸收不良或乳糖不耐受的关系]
Pol Merkur Lekarski. 2009 Feb;26(152):110-6.

引用本文的文献

1
Evaluation of a rapid breath hydrogen analyzer for clinical studies of carbohydrate absorption.用于碳水化合物吸收临床研究的快速呼气氢分析仪的评估
Dig Dis Sci. 1983 May;28(5):397-404. doi: 10.1007/BF02430527.
2
Oral intake of glucose plus galactose and erythrocyte galactose-1-phosphate. A nutritional evaluation of hydrolyzed lactose.口服葡萄糖加半乳糖与红细胞1-磷酸半乳糖。水解乳糖的营养评估。
Z Ernahrungswiss. 1986 Sep;25(3):171-9. doi: 10.1007/BF02021249.