Fass B, Lippe B M, Kaplan S A
Am J Dis Child. 1979 Sep;133(9):931-3. doi: 10.1001/archpedi.1979.02130090059010.
One hundred ninety-one children were tested by one of three screening procedures for growth hormone deficiency over a five-year period. Sleep screen yielded a 31.3% false-positive rate; levodopa administration alone yielded a 20.5% false-positive rate and levodopa in combination with propranolol yielded a 5.2% false-positive rate. These results support the view that the combined levodopa-propranolol hydrochloride screen test is superior to either the sleep or the levodopa screen tests in limiting the number of false-positive results and thus the need for further, more extensive testing.
在五年时间里，191名儿童接受了三种生长激素缺乏筛查程序中的一种检测。睡眠筛查的假阳性率为31.3%；单独使用左旋多巴的假阳性率为20.5%，左旋多巴与普萘洛尔联合使用的假阳性率为5.2%。这些结果支持这样一种观点，即在限制假阳性结果数量以及由此减少进一步进行更广泛检测的必要性方面，左旋多巴-盐酸普萘洛尔联合筛查试验优于睡眠或左旋多巴筛查试验。
