通过代谢物形成发挥作用的药物细胞毒性活性的组织培养评估方法。 - Suppr

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超能文献

Method for tissue culture evaluation of the cytoxic activity of drugs active through the formation of metabolites.

作者信息

Dolfini E, Martini A, Donnelli M G, Morasca L, Garattini S

出版信息

Eur J Cancer (1965). 1973 May;9(5):375-8. doi: 10.1016/0014-2964(73)90054-6.

DOI:10.1016/0014-2964(73)90054-6

PMID:4746736

Abstract

摘要

相似文献

Method for tissue culture evaluation of the cytoxic activity of drugs active through the formation of metabolites.通过代谢物形成发挥作用的药物细胞毒性活性的组织培养评估方法。

Eur J Cancer (1965). 1973 May;9(5):375-8. doi: 10.1016/0014-2964(73)90054-6.

[Comparison of the antimitotic properties of cyclophosphamide and its biotransformation products on meristema plant cells and animal cells in in vitro culture].[环磷酰胺及其生物转化产物对体外培养的植物分生组织细胞和动物细胞的抗有丝分裂特性比较]

C R Seances Soc Biol Fil. 1981;175(2):182-6.

Activation of cyclophosphamide for in vitro testing of cell sensitivity.用于细胞敏感性体外测试的环磷酰胺活化。

Cancer Res. 1980 Dec;40(12):4443-5.

Differential activation of cyclophosphamide and ifosphamide by cytochromes P-450 2B and 3A in human liver microsomes.细胞色素P-450 2B和3A在人肝微粒体中对环磷酰胺和异环磷酰胺的差异激活作用。

Cancer Res. 1993 Dec 1;53(23):5629-37.

Activation of cyclophosphamide by freeze-dried microsomes as an in vitro test of cytogenetic damage.通过冻干微粒体激活环磷酰胺作为细胞遗传损伤的体外试验。

Mutat Res. 1982 Dec;105(6):429-32. doi: 10.1016/0165-7992(82)90189-0.

[Immunosuppressant effect of cyclophosphamide activated in vitro by liver microsomes from different strains of mice].[不同品系小鼠肝脏微粒体体外激活环磷酰胺的免疫抑制作用]

Biull Eksp Biol Med. 1981 Jul;92(7):57-60.

Role of aldehyde dehydrogenase in the metabolism-dependent biological activity of cyclophosphamide.醛脱氢酶在环磷酰胺代谢依赖性生物学活性中的作用。

Cancer Res. 1981 Sep;41(9 Pt 1):3571-83.

The enzymatic basis of the selective action of cyclophosphamide.环磷酰胺选择性作用的酶学基础。

Cancer Res. 1975 Dec;35(12):3755-61.

Metabolizing systems in cell culture cytotoxicity tests.细胞培养细胞毒性试验中的代谢系统。

Xenobiotica. 1988 Jun;18(6):649-56. doi: 10.3109/00498258809041703.

Pharmacology of cyclophosphamide and metabolites.

Cancer Treat Rep. 1981;65 Suppl 3:89-95.

引用本文的文献

Pharmacologic studies of anticancer drugs with the human tumor stem cell assay.采用人肿瘤干细胞检测法对抗癌药物进行的药理学研究。

Cancer Chemother Pharmacol. 1981;6(3):253-64. doi: 10.1007/BF00256978.

Application of a microsomal drug activation system in a human tumor cloning assay.微粒体药物激活系统在人类肿瘤克隆试验中的应用。

Invest New Drugs. 1983;1(1):27-32. doi: 10.1007/BF00180189.

Comparative in vitro cytotoxicity of cyclophosphamide, its major active metabolites and the new oxazaphosphorine ASTA Z 7557 (INN mafosfamide).环磷酰胺、其主要活性代谢物及新型恶唑磷（国际非专利药品名称：马法兰磷酰胺）的体外细胞毒性比较

Invest New Drugs. 1984;2(2):141-8. doi: 10.1007/BF00232343.

[The effect of cyclophosphamide on tumors in the sensitivity-test (author's transl)].环磷酰胺对敏感性试验中肿瘤的作用（作者译）

Arch Gynakol. 1975;218(1):11-23. doi: 10.1007/BF00672279.

Assay of anti-cancer drugs in tissue culture: conditions affecting their ability to incorporate 3H-leucine after drug treatment.组织培养中抗癌药物的测定：药物处理后影响其掺入³H-亮氨酸能力的条件。

Br J Cancer. 1975 Jan;31(1):89-99. doi: 10.1038/bjc.1975.11.

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