Lee J S
Am J Physiol. 1979 Sep;237(3):E301-7. doi: 10.1152/ajpendo.1979.237.3.E301.
A newly developed intestinal preparation is described for determining lymph capillary pressure (PL) in the villi in vivo and in vitro. Determination of PL provided an estimate of tissue fluid pressure in the villi. PL was related to the fluid absorption rate and increased by lymphatic obstruction. During fluid absorption from isotonic mucosal fluid, PL was 1.4 +/- 0.5 or 1.1 +/- 0.4 cmH2O determined in vivo or in vitro, respectively. Both pressures were essentially in the same range as that (0.7 +/- 0.3--1.3 +/- 0.5 cmH2O) in which the mucosal fluid was isotonic Na2SO4 solution or Na-free solutions from which little fluid absorption occurred. This range of pressures may be taken as the normal tissue fluid pressure in the villi. At a high rate of fluid absorption from hypotonic mucosal fluid, PL increased to 5.2 +/- 1.4 cmH2O and tissue fluid pressure was also similarly increased. It is concluded that the fluid absorptive process by the epithelium could not develop an appreciable hydrostatic pressure in the villus tissue space or in the lymphatics.
本文描述了一种新开发的肠道制剂，用于在体内和体外测定绒毛中的淋巴管压力（PL）。PL的测定提供了绒毛中组织液压力的估计值。PL与液体吸收速率相关，并因淋巴管阻塞而升高。在从等渗粘膜液中吸收液体期间，体内和体外测定的PL分别为1.4±0.5或1.1±0.4 cmH₂O。这两个压力基本上与粘膜液为等渗Na₂SO₄溶液或几乎不发生液体吸收的无钠溶液时的压力范围（0.7±0.3 - 1.3±0.5 cmH₂O）相同。这个压力范围可被视为绒毛中的正常组织液压力。在从低渗粘膜液中高速率吸收液体时，PL升高至5.2±1.4 cmH₂O，组织液压力也同样升高。结论是上皮细胞的液体吸收过程不会在绒毛组织间隙或淋巴管中产生明显的静水压力。
