The determination of 7-chloro-1,3-dihydro-5-(2',chlorophenyl)-2H-1,4-benzodiazepin-2-one (Ro 5-3027) and its metabolite (lorazepam) in blood and urine by electron-capture gas liquid chromatography.

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作者信息

de Silva J A, Bekersky I, Puglisi C V

出版信息

J Chromatogr Sci. 1973 Oct;11(10):547-52. doi: 10.1093/chromsci/11.10.547.

DOI:10.1093/chromsci/11.10.547

PMID:4750858

Abstract

摘要

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The determination of 7-chloro-1,3-dihydro-5-(2',chlorophenyl)-2H-1,4-benzodiazepin-2-one (Ro 5-3027) and its metabolite (lorazepam) in blood and urine by electron-capture gas liquid chromatography.

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Pharmacokinetics and bioavailability of intravenous and oral chlordesmethyldiazepam in humans.氯地西泮静脉注射和口服给药在人体中的药代动力学及生物利用度

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